加热玉米油和 2,4-癸二烯醛可抑制人体的胃排空和能量摄入。

Heated Corn Oil and 2,4-Decadienal Suppress Gastric Emptying and Energy Intake in Humans.

机构信息

School of Health Sciences, Prefectural University of Hiroshima, 1-1-71 Ujina-higashi, Minami-ku, Hiroshima 734-8558, Japan.

J-Oil Mills, Inc., 7-41 Oogurocho, Tsurumi-ku, Yokohama 230-0053, Japan.

出版信息

Nutrients. 2021 Apr 15;13(4):1304. doi: 10.3390/nu13041304.

DOI:10.3390/nu13041304

PMID:33920888

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8071276/

Abstract

Consumption of 2,4-decadienal (2,4-DD) delays gastric emptying (GE) rate in animals. Oil heating produces 2,4-DD and other aldehydes. Here we examined whether heated oil affects GE rate and food intake in humans, and whether it is mediated by 2,4-DD. In the first experiment, 10 healthy volunteers consumed 240-g pumpkin soup with 9.2 g of heated (HO) or non-heated corn oil (CO). Subsequently, 17 participants consumed pumpkin soup containing 3.1 g of either heated corn oil (HO), 1 mg 2,4-DD + non-heated corn oil (2,4-DD), or non-heated corn oil (CO). Sixty minutes following pumpkin soup, cod roe spaghetti was provided, and then energy intake was determined. To evaluate GE rate, C breath test (Experiment 1) and ultrasonography (Experiments 1 and 2) were used. The results from the Experiment 1 confirmed that consumption of heated corn oil reduced GE rate. Experiment 2 showed a delayed GE rate in HO and 2,4-DD trials compared with CO trial ( < 0.05). Energy intake was approximately 600-650 kJ lower in HO and 2,4-DD trials compared with CO trial ( < 0.05). These findings suggest that 2,4-DD, either formed by oil heating or added to food, contributes to suppressing GE rate and energy intake.

摘要

食用 2,4-癸二烯醛（2,4-DD）会延迟动物的胃排空（GE）速度。油加热会产生 2,4-DD 和其他醛类。在这里，我们研究了加热油是否会影响人类的 GE 速度和食物摄入，以及它是否由 2,4-DD 介导。在第一个实验中，10 名健康志愿者食用了 240 克南瓜汤，其中含有 9.2 克加热（HO）或非加热玉米油（CO）。随后，17 名参与者食用了含有 3.1 克加热玉米油（HO）、1 毫克 2,4-DD+非加热玉米油（2,4-DD）或非加热玉米油（CO）的南瓜汤。在食用南瓜汤 60 分钟后，提供了鳕鱼鱼子酱意大利面，然后确定能量摄入。为了评估 GE 速度，使用 C 呼气试验（实验 1）和超声检查（实验 1 和 2）。实验 1 的结果证实，食用加热玉米油会降低 GE 速度。实验 2 表明，与 CO 试验相比，HO 和 2,4-DD 试验的 GE 速度延迟（<0.05）。与 CO 试验相比，HO 和 2,4-DD 试验的能量摄入约低 600-650 kJ（<0.05）。这些发现表明，2,4-DD，无论是由油加热形成还是添加到食物中，都会导致 GE 速度和能量摄入受到抑制。