Department of Biomedicine, Neuroscience and Advanced Diagnostic (BIND), University of Palermo, 90127 Palermo, Italy.
Department of Applied Clinical Sciences and Biotechnology, University of L'Aquila, 67100 L'Aquila, Italy.
Nutrients. 2021 Apr 19;13(4):1361. doi: 10.3390/nu13041361.
The restrictions taken to control the rapid spread of COVID-19 resulted in a sudden, unprecedented change in people's lifestyle, leading to negative consequences on general health. This study aimed to estimate the impact of such changes on migraine severity during 2020 March-May lockdown.
Patients affected by migraine with or without aura, diagnosed by expert physicians, completed a detailed interview comprehensive of: assessment of migraine characteristics; measure of physical activity (PA) levels; measure of the intake frequency of main Italian foods; the Insomnia Severity Index (ISI) questionnaire investigating sleep disorders.
We included 261 patients with a mean age of 44.5 ± 12.3 years. During social distancing, 72 patients (28%) reported a headache worsening, 86 (33%) an improvement, and 103 (39%) a stable headache frequency. A significant decrease of the PA levels during COVID-19 quarantine in the whole study sample was observed (median total metabolic equivalent task (METs) decreased from 1170 to 510; < 0.001). Additionally, a significant difference was reported on median ISI scores (from 7 to 8; < 0.001), which were increased in patients who presented a stable or worsening headache.
Our study confirmed that the restrictions taken during the pandemic have affected the practice of PA levels and sleep quality in migraine. Hence, PA and sleep quality should be assessed to find strategies for an improvement in quality of life.
为控制 COVID-19 的快速传播而采取的限制措施导致人们的生活方式突然发生前所未有的变化，对整体健康产生负面影响。本研究旨在评估 2020 年 3 月至 5 月封锁期间这种变化对偏头痛严重程度的影响。
受专家医生诊断患有偏头痛（有或无先兆）的患者完成了详细的访谈，其中包括：偏头痛特征评估；体力活动（PA）水平测量；主要意大利食物摄入频率测量；失眠严重程度指数（ISI）问卷调查睡眠障碍。
我们纳入了 261 名平均年龄为 44.5 ± 12.3 岁的患者。在社交隔离期间，72 名患者（28%）报告头痛加重，86 名（33%）报告头痛改善，103 名（39%）报告头痛频率稳定。在整个研究样本中，COVID-19 隔离期间的 PA 水平显著下降（总代谢当量任务（METs）中位数从 1170 降至 510；<0.001）。此外，ISI 评分中位数也有显著差异（从 7 降至 8；<0.001），在头痛稳定或加重的患者中评分增加。
我们的研究证实，大流行期间采取的限制措施影响了偏头痛患者的 PA 水平和睡眠质量。因此，应评估 PA 和睡眠质量，以寻找改善生活质量的策略。
