巴基斯坦旁遮普省零售市场玉米及其产品中脱氧雪腐镰刀菌烯醇水平的变化及其风险评估的估计。
Variation of Deoxynivalenol Levels in Corn and Its Products Available in Retail Markets of Punjab, Pakistan, and Estimation of Risk Assessment.
机构信息
Department of Applied Chemistry, Government College University Faisalabad, Faisalabad 38000, Pakistan.
Department of Food Science, Faculty of Food Science and Technology, Universiti Putra Malaysia (UPM), 43400 UPM Serdang, Selangor, Malaysia.
出版信息
Toxins (Basel). 2021 Apr 22;13(5):296. doi: 10.3390/toxins13050296.
This study investigated the natural incidence of deoxynivalenol (DON) in corn and corn products from corn-producing districts of Punjab, Pakistan. The analysis was carried out using high performance liquid chromatography (HPLC) with UV detector and immunoaffinity cleanup columns. The detection limit (LOD) and limit of quantification were 25 and 50 µg/kg, respectively. A total of 1220 samples of corn and corn products were analyzed to detect DON, and 539 (44.2%) samples were observed to be contaminated with DON ( ≥ LOD). Furthermore, 92 (7.5%) samples of corn and corn products had DON levels that were higher than the proposed limits of the EU. The data are significantly different from a normal distribution of DON in samples of corn and corn products from different locations ( < 0.05) for Shapiro-Wilk and Kolmogorov-Smirnov values. However, a significant difference in DON levels was found between corn and corn-derived products ( ≤ 0.05). The lowest and highest exposures, and hazard quotient (HQ) values of 0.92 and 9.68 µg/kg bw/day, were documented in corn flour samples.
本研究调查了巴基斯坦旁遮普省玉米产区玉米及其制品中脱氧雪腐镰刀菌烯醇（DON）的自然发生率。采用高效液相色谱法（HPLC）结合紫外检测器和免疫亲和净化柱进行分析。检测限（LOD）和定量限分别为 25 和 50 μg/kg。共分析了 1220 份玉米和玉米制品样本以检测 DON，其中 539 份（44.2%）样本被检出 DON（≥LOD）污染。此外，92 份（7.5%）玉米和玉米制品样本的 DON 含量高于欧盟规定的限量。玉米和玉米制品不同来源样本 DON 数据的 Shapiro-Wilk 和 Kolmogorov-Smirnov 值均呈正态分布差异显著（<0.05）。然而，玉米和玉米衍生产品之间 DON 水平存在显著差异（≤0.05）。在玉米粉样本中，记录到最低和最高暴露量以及危害系数（HQ）值分别为 0.92 和 9.68μg/kg bw/day。
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