Nicholas D S, Weller R O
Department of Neuropathology, Southampton University Medical School, England.
J Neurosurg. 1988 Aug;69(2):276-82. doi: 10.3171/jns.1988.69.2.0276.
The fine anatomy of the human spinal meninges was examined in five postmortem spinal cords taken within 12 hours after death from patients aged 15 months to 46 years. Specimens of spinal cord were viewed in transverse section and from the dorsal and ventral aspects by scanning electron microscopy. Transverse sections of spinal cord and meninges were also examined by light microscopy. The arachnoid mater was seen to be closely applied to the inner aspect of the dura. An intermediate fenestrated leptomeningeal layer was observed attached to the inner aspect of the arachnoid mater and was reflected ventrally to form a series of dorsal septa. As it arborized laterally over the surface of the cord to surround nerves and blood vessels, the intermediate layer became highly fenestrated but remained distinct from the pia and arachnoid mater. The pia mater appeared to form a continuous layer which was reflected off the surface of the cord to coat blood vessels within the subarachnoid space in a manner similar to that described in the leptomeninges over the human cerebral cortex. Each dentate ligament consisted of a collagenous core which was continuous with the subpial connective tissue and was attached at intervals to the dura; pia-arachnoid cells coated the surface of the dentate ligaments. The present study suggests that the fine anatomy of the human spinal meninges differs significantly from that described in other mammals.
对5例死亡时间在12小时内、年龄在15个月至46岁之间患者的死后脊髓进行了人体脊膜精细解剖结构的研究。通过扫描电子显微镜从横向、背侧和腹侧观察脊髓标本。脊髓和脊膜的横切片也通过光学显微镜进行检查。可见蛛网膜紧密贴附于硬脑膜的内侧面。观察到一层中间有窗孔的软脊膜层附着于蛛网膜的内侧面，并向腹侧折返形成一系列背侧隔。当它在脊髓表面横向分支以包围神经和血管时，中间层变得高度有窗孔，但仍与软膜和蛛网膜不同。软膜似乎形成一个连续的层，它从脊髓表面折返以包裹蛛网膜下腔内的血管，其方式类似于人类大脑皮质软脑膜中所描述的那样。每个齿状韧带由一个胶原核心组成，该核心与软膜下结缔组织连续，并间隔附着于硬脑膜；软膜-蛛网膜细胞覆盖齿状韧带的表面。本研究表明，人类脊膜的精细解剖结构与其他哺乳动物中所描述的有显著差异。
