功能磁共振成像在脑肿瘤术前定位中的作用。

Role of Functional Magnetic Resonance Imaging in the Presurgical Mapping of Brain Tumors.

机构信息

Division of Neuroradiology, The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA.

Division of Neuroradiology, The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA; Department of Neurosurgery, Johns Hopkins University School of Medicine, 1800 Orleans Street, Baltimore, MD 21287, USA.

出版信息

Radiol Clin North Am. 2021 May;59(3):377-393. doi: 10.1016/j.rcl.2021.02.001.

DOI:10.1016/j.rcl.2021.02.001

PMID:33926684

Abstract

When planning for brain tumor resection, a balance between maximizing resection and minimizing injury to eloquent brain parenchyma is paramount. The advent of blood oxygenation level-dependent functional magnetic resonance (fMR) imaging has allowed researchers and clinicians to reliably measure physiologic fluctuations in brain oxygenation related to neuronal activity with good spatial resolution. fMR imaging can offer a unique insight into preoperative planning for brain tumors by identifying eloquent areas of the brain affected or spared by the neoplasm. This article discusses the fMR imaging techniques and their applications in neurosurgical planning.

摘要

在规划脑肿瘤切除时，最大限度地切除肿瘤和最小化对语言相关脑实质的损伤之间需要取得平衡。血氧水平依赖功能磁共振成像（fMRI）的出现使得研究人员和临床医生能够以良好的空间分辨率可靠地测量与神经元活动相关的脑氧合生理波动。fMRI 可以通过识别受肿瘤影响或未受肿瘤影响的大脑语言区域，为脑肿瘤的术前规划提供独特的见解。本文讨论了 fMRI 技术及其在神经外科规划中的应用。