From the Department of Radiology (J.D.O., V.L.J), University of North Carolina, Chapel Hill, North Carolina.
From the Department of Radiology (J.D.O., V.L.J), University of North Carolina, Chapel Hill, North Carolina
AJNR Am J Neuroradiol. 2021 Jun;42(6):998-1007. doi: 10.3174/ajnr.A7079. Epub 2021 Apr 29.
This article will familiarize neuroradiologists with the pathophysiology, clinical findings, and standard MR imaging and PET imaging features of multiple forms of dementia as well as new emerging techniques. Cases were compiled from multiple institutions with the goal of improved diagnostic accuracy and improved patient care as well as information about biomarkers on the horizon. Dementia topics addressed include the following: Alzheimer disease, frontotemporal dementia, cerebral amyloid angiopathy, Lewy body dementia, Parkinson disease and Parkinson disease variants, amyotrophic lateral sclerosis, multisystem atrophy, Huntington disease vascular dementia, and Creutzfeldt-Jakob disease.
本文将使神经放射科医生熟悉多种形式痴呆的病理生理学、临床发现以及标准磁共振成像和正电子发射断层扫描成像特征,以及新出现的技术。这些病例是从多个机构收集的,目的是提高诊断准确性和改善患者护理,并了解即将出现的生物标志物信息。本文讨论的痴呆症主题包括以下内容:阿尔茨海默病、额颞叶痴呆、脑淀粉样血管病、路易体痴呆、帕金森病和帕金森病变异型、肌萎缩侧索硬化症、多系统萎缩、亨廷顿病、血管性痴呆和克雅氏病。