Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Local Health Unit (ULSS 2 Marca Trevigiana), Treviso, Italy.
Euro Surveill. 2021 Apr;26(17). doi: 10.2807/1560-7917.ES.2021.26.17.2100420.
Data on effectiveness of the BioNTech-/Pfizer COVID-19 vaccine in real-world settings are limited. In a study of 6,423 healthcare workers in Treviso Province, Italy, we estimated that, within the time intervals of 14-21 days from the first and at least 7 days from the second dose, vaccine effectiveness in preventing SARS-CoV-2 infection was 84% (95% confidence interval (CI): 40-96) and 95% (95% CI: 62-99), respectively. These results could support the ongoing vaccination campaigns by providing evidence for targeted communication.
有关真实环境中 BioNTech-/辉瑞 COVID-19 疫苗有效性的数据有限。在一项针对意大利特雷维索省 6423 名医护人员的研究中,我们估计,在第一剂后 14-21 天和第二剂后至少 7 天的时间间隔内,疫苗预防 SARS-CoV-2 感染的有效性分别为 84%(95%置信区间[CI]:40-96)和 95%(95%CI:62-99)。这些结果可以为有针对性的沟通提供证据,从而支持正在进行的疫苗接种活动。