Department of Life Sciences, School of Sciences, University of Management and Technology, Lahore, Pakistan.
Accident and Emergency Department, Shaikh Zayed Medical Hospital, Lahore, Pakistan.
Theor Biol Forum. 2020 Jan 1;113(1-2):47-54. doi: 10.19272/202011402005.
Sars-CoV-2 is a new global health challenge that was declared a pandemic in March 2020. In just 6 months, the virus had infected more than 7.5 million population worldwide, and in 10 months infected over 40 million. Clinical manifestation of Sars-CoV-2 range from mild symptoms like sneezing, coughing, cold and fever to severe respiratory complications such as pneumonia and acute distress respiratory syndrome, sepsis, and multiple organ failure. The virus is highly contagious and transmits through respiratory droplets. Currently, there is no treatment option available to treat Sars-CoV-2. Several research groups are working to explore different aspects of virus but further research is needed to fill the knowledge gaps. Herein, this review article provides latest update on genomic characterization, transmission, diagnosis, treatment, and clinical manifestation of Sars-CoV-2.
Sars-CoV-2 是一项新的全球健康挑战,已于 2020 年 3 月宣布为大流行。在短短 6 个月内,该病毒已在全球感染了超过 750 万人,在 10 个月内感染了超过 4000 万人。Sars-CoV-2 的临床症状从打喷嚏、咳嗽、感冒和发烧等轻微症状到肺炎和急性呼吸窘迫综合征、败血症和多器官衰竭等严重呼吸道并发症不等。该病毒具有高度传染性,通过呼吸道飞沫传播。目前,尚无治疗 Sars-CoV-2 的方法。一些研究小组正在努力探索病毒的不同方面,但需要进一步的研究来填补知识空白。本文综述了 Sars-CoV-2 的基因组特征、传播、诊断、治疗和临床表现的最新进展。