Key Laboratory of Chinese Materia Medica (Ministry of Education), Heilongjiang University of Chinese Medicine, Harbin, P.R. China.
Nat Prod Res. 2022 Jul;36(14):3579-3586. doi: 10.1080/14786419.2020.1869973. Epub 2021 Jan 10.
Four new polyacetylene substances, sadivaethynes A-D, were isolated from the ethanol extract of the roots of (Turcz.) Schischk using repeated column chromatography. Structural elucidation of compounds was established by 1D and 2D NMR spectra referring to the literature, together with high-resolution mass spectrometric analysis. All compounds were evaluated for cytotoxicity against two human cancer cell lines (MGC-803, Ishikawa) .
从(Turcz.)Schischk 的根的乙醇提取物中,通过反复柱层析分离得到了四个新的聚乙炔类物质,sadivaethynes A-D。通过参考文献的 1D 和 2D NMR 光谱以及高分辨率质谱分析,确定了化合物的结构。所有化合物均针对两种人癌细胞系(MGC-803、Ishikawa)进行了细胞毒性评估。