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和及其抗增殖活性的化学成分。

Chemical constituents from the and their antiproliferative activity.

机构信息

118437 Heilongjiang University of Chinese Medicine , Harbin, China.

Key Laboratory of Basic and Application Research of Beiyao (Heilongjiang University of Chinese Medicine), Ministry of Education, Harbin, China.

出版信息

Z Naturforsch C J Biosci. 2024 May 24;79(9-10):285-290. doi: 10.1515/znc-2024-0009. Print 2024 Sep 25.

Abstract

Nine compounds were isolated and identified from ethanolic extracts of , including one new alkaloid (), one new pentacyclic triterpenoid (), and seven known alkaloids (-). Structural elucidation of compounds and was established by 1D and 2D NMR spectra referring to the literature, together with high-resolution mass spectrometric analysis. All compounds were evaluated for antiproliferative activity against two cancer cell lines (LN229, A549) . Compounds (-) showed no significant antiproliferative activity.

摘要

从 中用乙醇提取得到了九种化合物,包括一种新的生物碱(),一种新的五环三萜()和七种已知的生物碱(-)。化合物和的结构通过参考文献的 1D 和 2D NMR 光谱以及高分辨率质谱分析确定。所有化合物均针对两种癌细胞系(LN229、A549)进行了抗增殖活性评估。化合物(-)没有显示出显著的抗增殖活性。

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