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MicroRNAs regulatory networks governing the epigenetic landscape of MEN1 gastro-entero-pancreatic neuroendocrine tumor: A case report.

作者信息

Luzi Ettore, Pandolfini Luca, Ciuffi Simone, Marini Francesca, Cremisi Federico, Nesi Gabriella, Brandi Maria Luisa

机构信息

Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy.

Istituto Italiano di Tecnologia (IIT), Genova, Italy.

出版信息

Clin Transl Med. 2021 Apr;11(4):e351. doi: 10.1002/ctm2.351.

DOI:10.1002/ctm2.351
PMID:33931963
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8023566/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f69/8023566/49ac8b6a4ac6/CTM2-11-e351-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f69/8023566/a952aa6e1ae1/CTM2-11-e351-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f69/8023566/969ce0a0e2f0/CTM2-11-e351-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f69/8023566/8bc7b8c813bd/CTM2-11-e351-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f69/8023566/49ac8b6a4ac6/CTM2-11-e351-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f69/8023566/a952aa6e1ae1/CTM2-11-e351-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f69/8023566/969ce0a0e2f0/CTM2-11-e351-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f69/8023566/8bc7b8c813bd/CTM2-11-e351-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f69/8023566/49ac8b6a4ac6/CTM2-11-e351-g002.jpg

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本文引用的文献

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microRNA-mediated noise processing in cells: A fight or a game?细胞中微小RNA介导的噪声处理：一场战斗还是一场游戏？
Comput Struct Biotechnol J. 2020 Mar 10;18:642-649. doi: 10.1016/j.csbj.2020.02.020. eCollection 2020.
2
FFLtool: a web server for transcription factor and miRNA feed forward loop analysis in human.FFLtool：一个用于人类转录因子和 miRNA 前馈回路分析的网络服务器。
Bioinformatics. 2020 Apr 15;36(8):2605-2607. doi: 10.1093/bioinformatics/btz929.
3
RNA Regulatory Networks as a Control of Stochasticity in Biological Systems.
Epigenetic Regulation in Gastroenteropancreatic Neuroendocrine Tumors.
胃肠胰神经内分泌肿瘤中的表观遗传调控
Front Oncol. 2022 Jun 7;12:901435. doi: 10.3389/fonc.2022.901435. eCollection 2022.
4
Role of miR-24 in Multiple Endocrine Neoplasia Type 1: A Potential Target for Molecular Therapy.miR-24 在多发性内分泌腺瘤病 1 型中的作用：一种潜在的分子治疗靶点。
Int J Mol Sci. 2021 Jul 8;22(14):7352. doi: 10.3390/ijms22147352.
作为生物系统随机性控制手段的RNA调控网络
Front Genet. 2019 May 7;10:403. doi: 10.3389/fgene.2019.00403. eCollection 2019.
4
Whole-genome landscape of pancreatic neuroendocrine tumours.胰腺神经内分泌肿瘤的全基因组图谱。
Nature. 2017 Mar 2;543(7643):65-71. doi: 10.1038/nature21063. Epub 2017 Feb 15.
5
NETs: organ-related epigenetic derangements and potential clinical applications.中性粒细胞胞外诱捕网：器官相关的表观遗传紊乱及其潜在临床应用
Oncotarget. 2016 Aug 30;7(35):57414-57429. doi: 10.18632/oncotarget.10598.
6
Thoracic and duodenopancreatic neuroendocrine tumors in multiple endocrine neoplasia type 1: natural history and function of menin in tumorigenesis.1 型多发性内分泌肿瘤中的胸和十二指肠胰腺神经内分泌肿瘤：menin 在肿瘤发生中的自然史和功能。
Endocr Relat Cancer. 2014 May 6;21(3):R121-42. doi: 10.1530/ERC-13-0482. Print 2014 Jun.
7
The negative feedback-loop between the oncomir Mir-24-1 and menin modulates the Men1 tumorigenesis by mimicking the "Knudson's second hit".抑癌基因 Mir-24-1 与 menin 之间的负反馈环通过模拟“Knudson 第二击”来调节 Men1 肿瘤发生。
PLoS One. 2012;7(6):e39767. doi: 10.1371/journal.pone.0039767. Epub 2012 Jun 27.
8
Multiple endocrine neoplasia type 1 (MEN1): not only inherited endocrine tumors.多发性内分泌腺瘤病 1 型（MEN1）：不仅仅是遗传性内分泌肿瘤。
Genet Med. 2009 Dec;11(12):825-35. doi: 10.1097/GIM.0b013e3181be5c97.