Department of Behavioral and Social Sciences, Brown University School of Public Health, 121 South Main St, Providence, RI, 02903, USA.
Johns Hopkins University, Baltimore, USA.
AIDS Behav. 2021 Nov;25(11):3482-3493. doi: 10.1007/s10461-021-03274-0. Epub 2021 May 1.
This study investigates PrEP willingness, adherence self-efficacy and potential impact of PrEP among HIV-negative, Chinese men who have sex with men (MSM; n = 622) with recent condomless anal sex. Facilitative factors of PrEP willingness included migrant status, sexual risk, and prior PrEP use, whereas barriers included concerns over being treated as an HIV/AIDS patient, recent HIV testing, identity concealment, and HIV prevention service usage. Adherence self-efficacy was associated with PrEP knowledge and confidence in PrEP efficacy of HIV prevention. A total of 39.3% anticipated increase in sex partners, 25.6% anticipated decrease in condom use, and 38.0% anticipated increased HIV testing following PrEP uptake. Results suggest a two-step approach to (1) promote PrEP acceptance among Chinese MSM and (2) enhance adherence and risk monitoring among PrEP-willing MSM. Efforts to reduce stigma, incorporate PrEP in the HIV prevention continuum, and increase PrEP knowledge will be crucial to optimize PrEP implementation.
本研究调查了最近有无保护肛交性行为的 HIV 阴性、男男性行为者（MSM；n=622）对 PrEP 的意愿、坚持自我效能感和潜在影响。PrEP 意愿的促进因素包括移民身份、性风险和之前的 PrEP 使用，而障碍包括担心被视为 HIV/AIDS 患者、最近的 HIV 检测、身份隐瞒和 HIV 预防服务使用。坚持自我效能感与 PrEP 知识和对 PrEP 预防 HIV 效果的信心相关。共有 39.3%的人预计性伴侣会增加，25.6%的人预计会减少 condom 使用，38.0%的人预计在开始使用 PrEP 后会增加 HIV 检测。结果表明，需要采取两步方法来（1）促进中国 MSM 对 PrEP 的接受度，（2）增强有意愿使用 PrEP 的 MSM 的坚持性和风险监测。减少污名化、将 PrEP 纳入 HIV 预防连续体以及增加 PrEP 知识的努力对于优化 PrEP 的实施至关重要。
