IRCCS Ospedale Policlinico San Martino, Genova, Genoa, Italy; Department of Health Sciences (DISSAL). University of Genoa, Genoa, Italy.
IRCCS Ospedale Policlinico San Martino, Genova, Genoa, Italy.
Eur J Radiol. 2021 Jun;139:109736. doi: 10.1016/j.ejrad.2021.109736. Epub 2021 Apr 26.
To compare ultrasound (US)-guided injections and surgery for the treatment of meralgia paresthetica (lateral femoral cutaneous neuropathy).
Two reviewers, independently, up to 10 October 2020 retrieved Studies that assessed the outcome of US-guided injections and surgery for the treatment of meralgia paresthetica from major medical libraries. Predefined inclusion and exclusion criteria were adopted.
399 studies were initially found, and the meta-analysis was conducted on 10 studies for a total of 149 patients. US-guided injections were done in three studies, surgery in seven studies. N = 38 % (57/149) of patients were treated with US-guided injection and 62 % (92/149) were treated with surgery. After US-guided injections, 85 % (49/57) of patients were treated successfully, whereas 80 % (74/92) were treated with surgery successfully from the clinical point of view. Differences were not statistically significant even with a slight heterogeneity of studies and outcome pooled on random-effect model. No comparative cohort study or RCT was conducted.
This meta-analysis showed that there was no statistically significant difference in treatment of meralgia paresthetica with ultrasound-guided injection or surgery. A RCT to compare a standardized US-guided approach versus surgery is essential to compare these techniques properly.
比较超声(US)引导下注射与手术治疗感觉异常性股痛(外侧股皮神经病变)。
两位审阅者于 2020 年 10 月 10 日之前,从主要医学文库中独立检索评估 US 引导下注射与手术治疗感觉异常性股痛的结局的研究。采用了预先设定的纳入和排除标准。
最初发现 399 项研究,对 10 项研究共 149 例患者进行了荟萃分析。三项研究中进行了 US 引导下注射,七项研究中进行了手术。38%(57/149)的患者接受 US 引导下注射治疗,62%(92/149)的患者接受手术治疗。US 引导下注射后,85%(49/57)的患者从临床角度来看治疗成功,而手术治疗的成功率为 80%(74/92)。即使存在研究和结局的轻度异质性,采用随机效应模型进行汇总,差异也无统计学意义。未进行比较队列研究或 RCT。
本荟萃分析表明,US 引导下注射与手术治疗感觉异常性股痛在统计学上无显著差异。需要进行 RCT 比较标准化 US 引导方法与手术,以正确比较这些技术。