Department of Radiology, National Institute for Cancer Research, Genoa, Italy.
J Ultrasound Med. 2011 Oct;30(10):1341-6. doi: 10.7863/jum.2011.30.10.1341.
The purposes of this study were to describe a technique for treatment of meralgia paresthetica (lateral femoral cutaneous neuropathy) using ultrasound guidance and to report the results of treatment.
Twenty consecutive patients (7 male and 13 female; age range, 23-66 years; mean, 39 years) with meralgia paresthetica confirmed by electromyography were treated with perineural injection of 1 mL of methylprednisolone acetate (40 mg/mL) and 8 mL of mepivacaine, 2%, under direct ultrasound guidance. Main outcome measures included the technical success of the procedure, visual analog scale score for the lateral femoral cutaneous nerve (pain, burning sensation, and paresthesia), and visual analog scale global quality of life score.
Technical success (successful nerve block at the distribution of the lateral femoral cutaneous nerve) was achieved in all patients. Five patients felt slight sharp pain during needle insertion. The symptoms in 16 patients (80%) diminished progressively after the first week. The 4 remaining patients (20%) required a further perineural injection. The symptoms disappeared in all patients 2 months after injection (mean visual analog scale score ± SD for lateral femoral cutaneous neuropathy at baseline, 8.1 ± 2.1; at 2 months, 2.1 ± 0.5; t = 6.2; P < .001). The mean visual analog scale quality of life scored decreased from 6.9 ± 3.2 to 2.3 ± 2.5 (t = 5.3; P < .002).
Treatment of meralgia paresthetica with ultrasound-guided perineural injections resulted in substantial symptom relief in most patients 2 months after injection. Randomized placebo-controlled trials of this treatment should be considered in the future.
本研究旨在描述一种使用超声引导治疗感觉异常性股痛(外侧股皮神经病变)的技术,并报告治疗结果。
20 例连续的感觉异常性股痛患者(7 名男性和 13 名女性;年龄 23-66 岁;平均 39 岁)通过肌电图证实存在感觉异常性股痛,在超声引导下对股外侧皮神经进行神经周围注射,注射药物包括 1 mL 醋酸甲泼尼龙(40 mg/mL)和 8 mL 2%甲哌卡因。主要观察指标包括操作技术的成功率、股外侧皮神经的视觉模拟评分(疼痛、烧灼感和感觉异常)以及视觉模拟总体生活质量评分。
所有患者均成功实施了该操作(股外侧皮神经分布区神经阻滞成功)。5 例患者在进针过程中感觉到轻微的锐痛。16 例患者(80%)的症状在第一周后逐渐减轻。其余 4 例患者(20%)需要再次进行神经周围注射。所有患者在注射后 2 个月症状消失(股外侧皮神经病的视觉模拟评分基线时为 8.1 ± 2.1,2 个月时为 2.1 ± 0.5;t = 6.2;P <.001)。平均视觉模拟生活质量评分从 6.9 ± 3.2 降至 2.3 ± 2.5(t = 5.3;P <.002)。
超声引导下的神经周围注射治疗感觉异常性股痛可在大多数患者注射后 2 个月内显著缓解症状。未来应考虑对此种治疗方法进行随机安慰剂对照试验。