Ahmed Mohammed S, Varrassi Giustino, Hadjiconstanti Despina, Zis Panagiotis
Medical School, University of Sheffield, Sheffield, UK.
Fondazione Paolo Procacci, Rome, Italy.
Pain Ther. 2025 Feb;14(1):103-119. doi: 10.1007/s40122-024-00693-4. Epub 2024 Dec 13.
Meralgia paresthetica (MP) is a sensory mononeuropathy affecting the lateral femoral cutaneous nerve. Diagnosis is typically made clinically, often utilising multiple diagnostic aids such as imaging and electrophysiology. Upon diagnosis, the management of MP follows the standard ladder, with conservative management first line, followed by steroid injection and finally surgery. Surgery may be neurolysis or neurectomy. A literature review of the PubMed database was performed identifying 594 papers regarding MP or the lateral femoral cutaneous nerve. Following a two-stage screening process and reference searching, 34 articles were included in this review, 11 discussing diagnosis and 23 discussing management. Despite the longstanding knowledge of MP, there remains limited comprehensive research discussing its diagnosis and management. Diagnosis of MP is based on clinical examination, imaging and electrophysiology. There is no obviously superior diagnostic strategy for MP. Once that diagnosis is made, the management strategy is typical of any condition, wherein a patient will move up the intervention ladder. It is apparent that conservative management and steroid injection are both adequate in most patients. Where these strategies fail, surgical options such as decompression, radiofrequency ablation or neurectomy are suitable for the majority of remaining patients. While both neurolysis and neurectomy are described as appropriate strategies, there is a scope for discussion regarding whether one is superior. Other management strategies such as botox, acupuncture and kinesio taping may have some value, but limited research exists on these strategies and further research into these is required.
股外侧皮神经感觉异常(MP)是一种影响股外侧皮神经的感觉性单神经病。诊断通常依靠临床进行,常需借助多种诊断辅助手段,如影像学和电生理检查。确诊后,MP的治疗遵循标准流程,首先采用保守治疗,其次是类固醇注射,最后是手术治疗。手术方式可以是神经松解术或神经切除术。我们对PubMed数据库进行了文献检索,共识别出594篇关于MP或股外侧皮神经的论文。经过两阶段筛选过程和参考文献检索,本综述纳入了34篇文章,其中11篇讨论诊断,23篇讨论治疗。尽管对MP的认识由来已久,但关于其诊断和治疗的全面研究仍然有限。MP的诊断基于临床检查、影像学和电生理检查。对于MP,没有明显更优的诊断策略。一旦确诊,治疗策略与其他疾病类似,即患者会按照干预级别逐步接受治疗。显然,大多数患者采用保守治疗和类固醇注射都足够。当这些策略失败时,减压、射频消融或神经切除术等手术选择适用于大多数剩余患者。虽然神经松解术和神经切除术都被认为是合适的策略,但关于哪种方法更优仍有讨论空间。肉毒杆菌毒素、针灸和肌内效贴布等其他治疗策略可能有一定价值,但关于这些策略的研究有限,需要进一步研究。