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[辐照绵羊血浆中自由基脂质氧化指标的评估]

[The estimate of the free-radical lipid oxidative indices of the blood plasma in irradiated sheep].

作者信息

Mirzoev E B, Kruglikov V P

出版信息

Radiats Biol Radioecol. 1995 Mar-Apr;35(2):189-94.

PMID:7757180
Abstract

External alpha-irradiation of sheep with doses of 51.6 and 154.8 mC/kg initiated free-radical oxidation of lipids in blood plasma, which was characterized by increase of spontaneous chemiluminescence intensity, malonaldehyde, conjugated diene and triene as well as of alpha-tocopherol concentration, while retinol level simultaneously decreased. On the contrary, chronic irradiation of sheep with doses of 2.58 and 12.9 mC/kg resulted in decrease of malonaldehyde content, conjugated diene and triene level as well as natural antioxidant alpha-tocopherol level in blood plasma.

摘要

以51.6和154.8毫库仑/千克的剂量对绵羊进行体外α射线照射,引发了血浆中脂质的自由基氧化,其特征是自发化学发光强度、丙二醛、共轭二烯和三烯以及α-生育酚浓度增加,而视黄醇水平同时下降。相反,以2.58和12.9毫库仑/千克的剂量对绵羊进行慢性照射,导致血浆中丙二醛含量、共轭二烯和三烯水平以及天然抗氧化剂α-生育酚水平降低。

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