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自身免疫性胰腺炎:一项单病例研究。

in autoimmune pancreatitis: A single-case study.

作者信息

Patil Rajkala P, Patil Panchakshari D, Thakar Anup B

机构信息

Department of Panchakarma, Central Ayurveda Research Institute for Cardiovascular Diseases, Punjabi Bagh, India.

Publication Section, Central Council for Research in Ayurvedic Sciences, Janakpuri, New Delhi, India.

出版信息

Ayu. 2019 Oct-Dec;40(4):242-246. doi: 10.4103/ayu.AYU_15_20. Epub 2021 Jan 14.

Abstract

Autoimmune pancreatitis (AIP) is the pancreatic manifestation of a systemic fibro-inflammatory disorder. AIP is a unique form of pancreatitis in which autoimmune mechanisms are suspected to be involved in the pathogenesis. AIP is a rare disorder, its exact cause is unknown, but it is thought to be caused by the body's immune system attacking the pancreas and it responds to steroid therapy only. In Ayurveda, although there is no synonym for AIP, but has a resemblance in clinical features of (derangement of duodenum and intestine). The cause of is (hypofunctioning of ) and therapy increases . As per Charaka Samhita, treatment for amongst the therapy is (therapeutic purgation) and (medicated enema). The present case report is of a 30-year-old female, diagnosed as case of AIP with multisystem involvement with increased level of immunoglobulin G (IgG), glycosylated heamoglobin (HbA1c), cholesterol, triglycerides, low-density lipoprotein (LDL) and body mass index (BMI). The patient was on anticholinergic agents, antacids, levothyroxine, multivitamin along with iron and antihistamine drugs since 1 year, but with not much relief. Patient was treated with classical and . It was observed after the completion of therapy, that there was decrease in IgG, HbA1c, S. cholesterol, S. triglyceride, low density lipoprotein (LDL) and body mass index (BMI). This shows that and play a significant role in patient with AIP associated with other disorders.

摘要

自身免疫性胰腺炎(AIP)是一种系统性纤维炎症性疾病的胰腺表现。AIP是胰腺炎的一种独特形式,其发病机制疑似涉及自身免疫机制。AIP是一种罕见疾病,确切病因不明,但被认为是由人体免疫系统攻击胰腺所致,且仅对类固醇治疗有反应。在阿育吠陀医学中,虽然没有与AIP同义的病症,但在临床特征上(十二指肠和肠道功能紊乱)有相似之处。其病因是(功能减退),而治疗会增加。根据《阇罗迦本集》,在治疗中针对的疗法是(治疗性泻下)和(药用灌肠)。本病例报告的是一名30岁女性,被诊断为AIP且有多系统受累,伴有免疫球蛋白G(IgG)、糖化血红蛋白(HbA1c)、胆固醇、甘油三酯、低密度脂蛋白(LDL)和体重指数(BMI)升高。该患者自1年来一直在服用抗胆碱能药物、抗酸剂、左甲状腺素、多种维生素以及铁剂和抗组胺药物,但缓解效果不佳。患者接受了经典的和治疗。治疗结束后观察到,IgG、HbA1c、血清胆固醇、血清甘油三酯、低密度脂蛋白(LDL)和体重指数(BMI)均有所下降。这表明和在伴有其他病症的AIP患者中发挥着重要作用。

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