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儿童疫苗犹豫与抗体检测的应用:一种对 COVID-19 有影响的新策略

Pediatric Vaccine Hesitancy and the Utilization of Antibody Measurements: A Novel Strategy with Implications for COVID 19.

作者信息

Dosanjh Amrita

机构信息

Pediatric Respiratory, San Diego, CA, USA.

Dove Medical Press, Auckland, New Zealand.

出版信息

J Asthma Allergy. 2021 Apr 23;14:427-431. doi: 10.2147/JAA.S303309. eCollection 2021.

DOI:10.2147/JAA.S303309
PMID:33935504
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8080153/
Abstract

Vaccine hesitancy is a well researched area with implications for both public health and the health of children and their families The factors leading to vaccine hesitancy are often complex and involve fear of the healthcare system and the process of vaccine development, cultural viewpoints and experiences. Pediatric patients often rely on parental guidance and decision making, and this may result in a lack of immunization for some children. The availability of the COVID 19 vaccine has been widely anticipated, yet not all individuals will seek the vaccine. Once vaccines are available for children under the age of 16 years, this long-standing pediatric management issue may again emerge and impact public health. The clinical trial efficacy and safety data for children and adolescents less than 16 years of age are not yet available. A traditional approach is to discuss the concerns of the parent in relationship to presentation and review of American Association of Pediatrics (AAP) and CDC guidelines in the framework of medical and scientific explanations. This includes the presentation of efficacy and safety data. Therefore, the use of lab-based antibody testing adds scientific evidence and emphasizes the need for vaccination against SARS CoV-2 and other pathogens. The purpose of this commentary is to propose lab-based testing as a potential adjunctive strategy in addressing this public health concern. Further study of a pediatric population is required to assess the impact of the selective use of lab-based testing in improving vaccination rates among a pediatric population.

摘要

疫苗犹豫是一个经过充分研究的领域,对公共卫生以及儿童及其家庭的健康都有影响。导致疫苗犹豫的因素通常很复杂,涉及对医疗系统和疫苗研发过程的恐惧、文化观念和经历。儿科患者往往依赖父母的指导和决策,这可能导致一些儿童无法接种疫苗。新冠疫苗的供应一直备受期待,但并非所有人都会寻求接种。一旦16岁以下儿童可以接种疫苗,这个长期存在的儿科管理问题可能会再次出现并影响公共卫生。目前尚无16岁以下儿童和青少年的临床试验疗效和安全性数据。传统方法是在医学和科学解释的框架内,讨论家长对美国儿科学会(AAP)和疾病控制与预防中心(CDC)指南的呈现和审查的担忧。这包括呈现疗效和安全性数据。因此,基于实验室的抗体检测增加了科学证据,并强调了针对严重急性呼吸综合征冠状病毒2(SARS-CoV-2)和其他病原体进行疫苗接种的必要性。本评论的目的是提出基于实验室的检测作为解决这一公共卫生问题的潜在辅助策略。需要对儿科人群进行进一步研究,以评估选择性使用基于实验室的检测对提高儿科人群疫苗接种率的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aedb/8080153/64ab7474e680/JAA-14-427-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aedb/8080153/64ab7474e680/JAA-14-427-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aedb/8080153/64ab7474e680/JAA-14-427-g0001.jpg

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