Suppr超能文献

糠酸莫米松鼻喷雾剂缓解儿童腺样体扁桃体切除术后疼痛的前瞻性对照研究

Nasal Sprays Containing Mometasone Furoate for Relief of Post-Adenotonsillectomy Pain in Children: A Prospective Controlled Study.

作者信息

Unsal Ozlem, Akpinar Meltem, Bozkurt Gulpembe, Soytas Pinar, Ekici Merve, Turk Bilge, Coskun Berna Uslu

机构信息

Department of Otorhinolaryngology Head and Neck Surgery, University of Health Sciences Turkey, Sisli Hamidiye Etfal Teaching and Research Hospital, Istanbul, Turkey.

Department of Otorhinolaryngology Head and Neck Surgery, Acibadem University Atakoy Hospital, Istanbul, Turkey.

出版信息

Sisli Etfal Hastan Tip Bul. 2021 Mar 17;55(1):101-107. doi: 10.14744/SEMB.2020.75735. eCollection 2021.

Abstract

OBJECTIVES

Adenotonsillectomy is one of most common surgeries performed in childhood. Post-operative pain associated particularly with tonsillectomy is still a problem for many physicians. Despite advances in surgical techniques, analgesics, or anti-inflammatory drugs, no unique strategy for post-tonsillectomy pain management has been suggested. The aim of this study is to investigate the analgesic effect of steroid containing nasal spray applied to tonsillar region after tonsillectomy.

METHODS

Eighty-two patients were assigned into two groups as study and control. In study group, nasal spray containing steroid was applied to each tonsillar region after surgery for 5 days. Post-operative pain of all patients was assessed using a visual analog scale and results were compared.

RESULTS

Pain decreased gradually over time in both the study and control groups. Although the pain scores from 4 h post-surgery to post-operative day 5 were not found to significantly decrease in children that used nasal spray containing steroid, these patients developed less pain on post-operative day 5,with statistical significance (p<0.05).

CONCLUSION

Post-tonsillectomy pain was reported to increase around post-operative day 5, which coincides with the time of intense wound inflammation. Therefore, significant pain reduction on post-operative day 5 observed in children that used nasal spray with steroid may have clinical importance for overcoming this problem.

摘要

目的

腺样体扁桃体切除术是儿童期最常见的手术之一。术后疼痛,尤其是扁桃体切除术后的疼痛,对许多医生来说仍是一个问题。尽管手术技术、镇痛药或抗炎药有所进步,但尚未提出针对扁桃体切除术后疼痛管理的独特策略。本研究的目的是探讨扁桃体切除术后在扁桃体区域应用含类固醇鼻喷雾剂的镇痛效果。

方法

82例患者被分为研究组和对照组。研究组在术后5天对每个扁桃体区域应用含类固醇的鼻喷雾剂。使用视觉模拟量表评估所有患者的术后疼痛情况并比较结果。

结果

研究组和对照组的疼痛均随时间逐渐减轻。虽然在使用含类固醇鼻喷雾剂的儿童中,术后4小时至术后第5天的疼痛评分未发现明显降低,但这些患者在术后第5天疼痛减轻,具有统计学意义(p<0.05)。

结论

据报道,扁桃体切除术后疼痛在术后第5天左右会加重,这与伤口强烈炎症的时间相吻合。因此,在使用含类固醇鼻喷雾剂的儿童中观察到术后第5天疼痛显著减轻,这对于克服这一问题可能具有临床重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/202c/8085455/89b4785e1095/MBSEH-55-101-g001.jpg

相似文献

1
Nasal Sprays Containing Mometasone Furoate for Relief of Post-Adenotonsillectomy Pain in Children: A Prospective Controlled Study.
Sisli Etfal Hastan Tip Bul. 2021 Mar 17;55(1):101-107. doi: 10.14744/SEMB.2020.75735. eCollection 2021.
2
Effects of intranasal mometasone furoate on itchy ear and palate in patients with seasonal allergic rhinitis.
Ann Allergy Asthma Immunol. 2012 May;108(5):359-62. doi: 10.1016/j.anai.2012.02.023. Epub 2012 Mar 23.
4
[Clinical observation of mometasone furoate nasal spray combined with montelukast sodium in the treatment of adenoid hypertrophy in children].
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2017 Mar 5;31(5):366-368. doi: 10.13201/j.issn.1001-1781.2017.05.009.
5
Role of mometasone furoate aqueous nasal spray for management of adenoidal hypertrophy in children.
J Laryngol Otol. 2014 Dec;128(12):1060-6. doi: 10.1017/S0022215114002503. Epub 2014 Nov 18.
7
The effects of dexamethasone, bupivacaine and topical lidocaine spray on pain after tonsillectomy.
Int J Pediatr Otorhinolaryngol. 2003 Jul;67(7):737-42. doi: 10.1016/s0165-5876(03)00091-0.
10
Effect of Topical Propolis on Wound Healing Process After Tonsillectomy: Randomized Controlled Study.
Clin Exp Otorhinolaryngol. 2018 Jun;11(2):146-150. doi: 10.21053/ceo.2017.00647. Epub 2017 Dec 28.

本文引用的文献

1
Control of Pain After Tonsillectomy in Children: A Review.
JAMA Otolaryngol Head Neck Surg. 2017 Sep 1;143(9):937-942. doi: 10.1001/jamaoto.2017.0845.
2
The Efficacy of Levobupivacaine Hydrochloride-Dexamethasone Infiltration for Post-Tonsillectomy Pain in Adults.
J Craniofac Surg. 2015 Oct;26(7):e651-3. doi: 10.1097/SCS.0000000000001975.
3
Causes, costs, and risk factors for unplanned return visits after adenotonsillectomy in children.
Int J Pediatr Otorhinolaryngol. 2015 Oct;79(10):1640-6. doi: 10.1016/j.ijporl.2015.07.002. Epub 2015 Jul 11.
4
Causes and costs for ED visits after pediatric adenotonsillectomy.
Otolaryngol Head Neck Surg. 2015 Apr;152(4):691-6. doi: 10.1177/0194599815572123. Epub 2015 Mar 2.
5
Comparison of local and intravenous dexamethasone for postoperative pain and recovery after tonsillectomy.
Otolaryngol Head Neck Surg. 2015 Mar;152(3):530-5. doi: 10.1177/0194599814567856. Epub 2015 Jan 20.
6
Ropivacaine plus dexamethasone infiltration reduces postoperative pain after tonsillectomy and adenoidectomy.
Int J Pediatr Otorhinolaryngol. 2013 Nov;77(11):1881-5. doi: 10.1016/j.ijporl.2013.08.037. Epub 2013 Sep 8.
7
Tonsillectomy healing.
Ann Otol Rhinol Laryngol. 2012 Oct;121(10):645-9. doi: 10.1177/000348941212101004.
8
Effect of dexamethasone on nausea, vomiting, and pain in paediatric tonsillectomy.
Br J Anaesth. 2012 Sep;109(3):427-31. doi: 10.1093/bja/aes249.
9
Topical bupivacaine compared to lidocaine with epinephrine for post-tonsillectomy pain relief in children: a randomized controlled study.
Int J Pediatr Otorhinolaryngol. 2011 Jan;75(1):77-80. doi: 10.1016/j.ijporl.2010.10.013. Epub 2010 Nov 10.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验