Tan Grace X, Tunkel David E
Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
JAMA Otolaryngol Head Neck Surg. 2017 Sep 1;143(9):937-942. doi: 10.1001/jamaoto.2017.0845.
The relief of pain after tonsillectomy in children remains challenging and even controversial. While the need for pain control after this surgery is understood, recent debate has centered around the risks of opioids in children with obstructive sleep apnea syndrome (OSAS) and the possible increases in posttonsillectomy hemorrhage with the use of alternative nonsteroidal anti-inflammatory drugs (NSAIDs).
We discuss the multiple facets of posttonsillectomy pain control in children. A variety of pharmacologic and nonpharmacologic interventions used before, during, and after surgery are reviewed, presenting the evidence for efficacy and possible adverse effects. We also review the various surgical techniques used in tonsillectomy with a focus on reducing postoperative pain.
Clinicians should understand effective methods of analgesia after tonsillectomy in children, and know the potential consequences of each option. Caution should be employed when using opioids, particularly in young children with severe OSAS. Although large studies of NSAID use have shown effective pain management without an increase in posttonsillectomy bleeding frequency, the potential for more severe bleeding events has been debated. Cold dissection techniques lead to less pain, but hot techniques remain popular, with less intraoperative blood loss and shorter operative time. Partial (intracapsular) tonsillectomy seems to reduce pain as well.
儿童扁桃体切除术后的疼痛缓解仍然具有挑战性,甚至存在争议。虽然人们理解该手术后疼痛控制的必要性,但最近的争论集中在阻塞性睡眠呼吸暂停综合征(OSAS)患儿使用阿片类药物的风险以及使用替代性非甾体抗炎药(NSAIDs)可能增加扁桃体切除术后出血的问题上。
我们讨论了儿童扁桃体切除术后疼痛控制的多个方面。回顾了手术前、手术中和手术后使用的各种药物和非药物干预措施,阐述了其疗效证据和可能的不良反应。我们还回顾了扁桃体切除术中使用的各种手术技术,重点是减少术后疼痛。
临床医生应了解儿童扁桃体切除术后有效的镇痛方法,并知晓每种选择的潜在后果。使用阿片类药物时应谨慎,尤其是对于患有严重OSAS的幼儿。尽管关于使用NSAIDs的大型研究表明其能有效控制疼痛且不增加扁桃体切除术后出血频率,但更严重出血事件的可能性仍存在争议。冷剥离技术导致的疼痛较轻,但热技术仍然很受欢迎,因为术中失血较少且手术时间较短。部分(囊内)扁桃体切除术似乎也能减轻疼痛。