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Adenosine and Kynurenic Acid Interactions: Possible Relevance for Schizophrenia Treatment?

作者信息

Beggiato Sarah, Zuccarini Mariachiara, Cassano Tommaso, Borroto-Escuela Dasiel Oscar, Di Iorio Patrizia, Schwarcz Robert, Fuxe Kjell, Ferraro Luca

机构信息

Department of Medical, Oral and Biotechnological Sciences, University of Chieti-Pescara, Chieti, Italy.

Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.

出版信息

Front Pharmacol. 2021 Apr 14;12:654426. doi: 10.3389/fphar.2021.654426. eCollection 2021.

DOI:10.3389/fphar.2021.654426
PMID:33935767
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8080066/
Abstract
摘要

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本文引用的文献

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Kynurenine Pathway of Tryptophan Metabolism in Neuropsychiatric Disorders: Pathophysiologic and Therapeutic Considerations.神经精神疾病中色氨酸代谢的犬尿氨酸途径：病理生理与治疗考量
Clin Psychopharmacol Neurosci. 2020 Nov 30;18(4):507-526. doi: 10.9758/cpn.2020.18.4.507.
2
Decreased striatal adenosine A-dopamine D receptor heteromerization in schizophrenia.精神分裂症中纹状体腺苷A-多巴胺D受体异聚体减少。
Neuropsychopharmacology. 2021 Feb;46(3):665-672. doi: 10.1038/s41386-020-00872-9. Epub 2020 Oct 3.
3
N-Acetylcysteine Inhibits Kynurenine Aminotransferase II.N-乙酰半胱氨酸抑制犬尿氨酸转氨酶II。
Neuroscience. 2020 Sep 15;444:160-169. doi: 10.1016/j.neuroscience.2020.07.049. Epub 2020 Aug 5.
4
Multiple Adenosine-Dopamine (A2A-D2 Like) Heteroreceptor Complexes in the Brain and Their Role in Schizophrenia.脑内多种腺苷-多巴胺（A2A-D2 样）异源受体复合物及其在精神分裂症中的作用。
Cells. 2020 Apr 27;9(5):1077. doi: 10.3390/cells9051077.
5
Potential antipsychotic action of the selective agonist of adenosine A1 receptors, 5'-Cl-5'-deoxy-ENBA, in amphetamine and MK-801 rat models.选择性腺苷 A1 受体激动剂 5'-Cl-5'-脱氧 ENBA 在安非他命和 MK-801 大鼠模型中的潜在抗精神病作用。
Pharmacol Rep. 2020 Jun;72(3):580-588. doi: 10.1007/s43440-020-00093-3. Epub 2020 Mar 26.
6
Activation of alpha7 nicotinic and NMDA receptors is necessary for performance in a working memory task.α7 型烟碱型乙酰胆碱受体和 NMDA 受体的激活对于工作记忆任务的表现是必要的。
Psychopharmacology (Berl). 2020 Jun;237(6):1723-1735. doi: 10.1007/s00213-020-05495-y. Epub 2020 Mar 11.
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