拉帕替尼和曲妥珠单抗双重HER2阻断联合化疗用于转移性胃食管腺癌
Dual HER2 blockade with lapatinib and trastuzumab in combination with chemotherapy in metastatic gastroesophageal adenocarcinoma.
作者信息
Cheong E Von, Ho Gwo Fuang
机构信息
Department of Clinical Oncology Menara Timur University of Malaya Medical Centre Kuala Lumpur Malaysia.
Faculty of Medicine University of Malaya Kuala Lumpur Malaysia.
出版信息
Clin Case Rep. 2021 Mar 5;9(4):2264-2268. doi: 10.1002/ccr3.4009. eCollection 2021 Apr.
Abstract
The development of resistance to trastuzumab in HER2-positive gastroesophageal cancer remains a problem. The use of dual HER2 blockade to overcome this is a therapeutic strategy that should be researched more extensively.
摘要
HER2阳性胃食管癌中曲妥珠单抗耐药的发展仍然是一个问题。使用双重HER2阻断来克服这一问题是一种治疗策略，应进行更广泛的研究。
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