患有格雷夫斯病的母亲，其胎儿甲状腺肿在甲状腺功能减退和甲状腺功能亢进之间交替的产前管理。
Prenatal management of fetal goiter alternating between hypothyroidism and hyperthyroidism in a mother with Graves' disease.
作者信息
Didier-Mathon Hortense, Bouchghoul Hanane, Senat Marie-Victoire, Young Jacques, Luton Dominique
机构信息
Department of Obstetrics and Gynecology FHU Prematurity Bichat Hospital Assistance publique-Hôpitaux de Paris Paris University Paris France.
Department of Obstetrics and Gynecology Assistance publique-Hôpitaux de Paris Bicêtre Hospital Le Kremlin-Bicêtre France.
出版信息
Clin Case Rep. 2021 Mar 4;9(4):2281-2284. doi: 10.1002/ccr3.4012. eCollection 2021 Apr.
We present a rare documented case with consecutive hypo- and hyperthyroidism during fetal life. First, hypothyroidism was due to transplacental passage of antithyroid drugs. After the mother's thyroidectomy, fetal hyperthyroidism was due to transplacental passage of persistent anti-thyrotropin receptor antibodies. Fetal goiter disappeared after adjusting maternal treatment.
我们报告了一例罕见的有记录的病例，胎儿期先后出现甲状腺功能减退和亢进。首先，甲状腺功能减退是由于抗甲状腺药物经胎盘传递所致。母亲甲状腺切除术后，胎儿甲状腺功能亢进是由于持续存在的抗促甲状腺素受体抗体经胎盘传递所致。调整母亲的治疗后，胎儿甲状腺肿消失。
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