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一名急性髓系白血病患者发生播散性真菌感染。

Disseminated fungal infection in a patient with acute myeloid leukemia.

作者信息

Duarte Delfim, Morais Cátia Iracema, Azevedo Rosa, Coelho Fernando, Martins Anabela, Pereira Brigitte, Coelho Sara, Domingues Nelson, Lebre Ana, Trigo Filipe, Romero Iracema, Guimarães Maria Augusta, Mariz José Mário, Faria Filomena

机构信息

Intensive Care Unit Portuguese Institute of Oncology-Porto Porto Portugal.

Department of Onco-Hematology Portuguese Institute of Oncology-Porto Porto Portugal.

出版信息

Clin Case Rep. 2021 Feb 26;9(4):2489-2491. doi: 10.1002/ccr3.3993. eCollection 2021 Apr.

DOI:10.1002/ccr3.3993
PMID:33936726
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8077245/
Abstract

The case highlights the importance of actively obtaining informative samples at an early stage and of prompt initiation of combination therapy with antifungal drugs.

摘要

该病例凸显了在早期积极获取信息性样本以及迅速启动抗真菌药物联合治疗的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37ab/8077245/56bd062a98d3/CCR3-9-2489-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37ab/8077245/56bd062a98d3/CCR3-9-2489-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37ab/8077245/56bd062a98d3/CCR3-9-2489-g001.jpg

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本文引用的文献

1
Prospective Evaluation of Serum β-Glucan Testing in Patients With Probable or Proven Fungal Diseases.对疑似或确诊真菌病患者血清β-葡聚糖检测的前瞻性评估。
Open Forum Infect Dis. 2016 Jun 16;3(3):ofw128. doi: 10.1093/ofid/ofw128. eCollection 2016 Sep.
2
Geotrichum capitatum septicaemia in a haematological patient after acute myeloid leukaemia relapse: identification using MALDI-TOF mass spectrometry and review of the literature.急性髓系白血病复发后血液学患者的头状地霉败血症：使用基质辅助激光解吸电离飞行时间质谱进行鉴定并文献复习
Infez Med. 2015 Jun;23(2):161-7.
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Revised definitions of invasive fungal disease from the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) Consensus Group.
欧洲癌症研究与治疗组织/侵袭性真菌感染合作组和美国国立过敏与传染病研究所真菌病研究组（EORTC/MSG）共识组对侵袭性真菌病的修订定义。
Clin Infect Dis. 2008 Jun 15;46(12):1813-21. doi: 10.1086/588660.
4
Contribution of the (1-->3)-beta-D-glucan assay for diagnosis of invasive fungal infections.（1→3）-β-D-葡聚糖检测对侵袭性真菌感染诊断的贡献
J Clin Microbiol. 2008 Mar;46(3):1009-13. doi: 10.1128/JCM.02091-07. Epub 2007 Dec 26.
5
Combined voriconazole plus caspofungin therapy for the treatment of probable Geotrichum pneumonia in a leukemia patient.伏立康唑联合卡泊芬净治疗白血病患者疑似地霉属肺炎
Infection. 2008 Feb;36(1):65-7. doi: 10.1007/s15010-007-6235-4. Epub 2007 Oct 9.
6
Invasive infections caused by Trichosporon species and Geotrichum capitatum in patients with hematological malignancies: a retrospective multicenter study from Italy and review of the literature.血液系统恶性肿瘤患者中由毛孢子菌属和头状地霉引起的侵袭性感染：一项来自意大利的回顾性多中心研究及文献综述
J Clin Microbiol. 2005 Apr;43(4):1818-28. doi: 10.1128/JCM.43.4.1818-1828.2005.
7
In vitro susceptibility testing of Geotrichum capitatum: comparison of the E-test, disk diffusion, and Sensititre colorimetric methods with the NCCLS M27-A2 broth microdilution reference method.头状地霉的体外药敏试验：E-test、纸片扩散法和Sensititre比色法与NCCLS M27-A2肉汤微量稀释参考方法的比较
Antimicrob Agents Chemother. 2003 Dec;47(12):3985-8. doi: 10.1128/AAC.47.12.3985-3988.2003.