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孤立性视网膜前膜:保留黄斑中心凹的内界膜剥除术的一种罕见并发症。

Isolated Central Epiretinal Membrane: A Rare Complication of Fovea-Sparing Internal Limiting Membrane Peeling Technique.

作者信息

Chen Yen-Chih, Chen San-Ni

机构信息

Department of Ophthalmology, Changhua Christian Hospital, Changhua, Taiwan.

Department of Ophthalmology, Yunlin Christian Hospital, Xiluo, Yunlin, Taiwan.

出版信息

J Ophthalmol. 2021 Apr 14;2021:6654604. doi: 10.1155/2021/6654604. eCollection 2021.

DOI:10.1155/2021/6654604
PMID:33936809
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8062195/
Abstract

PURPOSE

To report a rare complication presenting as an isolated central epiretinal membrane (ERM) related to fovea-sparing internal limiting membrane (ILM) peeling technique.

METHODS

Five patients who received fovea-sparing ILM peeling were enrolled. Postoperatively, an isolated central ERM developed. Optical coherence tomography (OCT) was used to evaluate the serial anatomic change.

RESULTS

Among the five included patients, one patient had high myopia with foveoschisis, two patients had vitreomacular traction, and two patients had proliferative diabetic retinopathy with tractional retinal detachment and a fovea cyst. With an average of 5.80 months, OCT showed the gradual development of the isolated central ERM with severe fovea distortion. Four patients received secondary revision surgery, with improvement of the fovea contour and visual acuity.

CONCLUSION

The fovea-sparing ILM peeling technique may cause a rare but serious complication as the isolated central ERM, which would cause significant fovea distortion as well as visual deterioration. Timely detection and intervention is recommended to prevent further visual loss. This trial is registered with NCT04445142.

摘要

目的

报告一种罕见的并发症,表现为与保留黄斑中心凹的内界膜(ILM)剥除术相关的孤立性黄斑中心视网膜前膜(ERM)。

方法

纳入5例接受保留黄斑中心凹ILM剥除术的患者。术后出现了孤立性黄斑中心ERM。采用光学相干断层扫描(OCT)评估一系列解剖学变化。

结果

在纳入的5例患者中,1例为高度近视合并黄斑劈裂,2例为玻璃体黄斑牵拉,2例为增殖性糖尿病视网膜病变合并牵拉性视网膜脱离及黄斑囊肿。平均5.80个月时,OCT显示孤立性黄斑中心ERM逐渐发展,黄斑中心凹严重变形。4例患者接受了二次修复手术,黄斑中心凹轮廓和视力得到改善。

结论

保留黄斑中心凹的ILM剥除术可能导致一种罕见但严重的并发症,即孤立性黄斑中心ERM,这会导致黄斑中心凹显著变形以及视力下降。建议及时检测和干预以防止进一步的视力丧失。本试验已在ClinicalTrials.gov注册,注册号为NCT04445142。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4cd7/8062195/6c5aee7649d3/joph2021-6654604.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4cd7/8062195/44db843f34ea/joph2021-6654604.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4cd7/8062195/6c5aee7649d3/joph2021-6654604.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4cd7/8062195/44db843f34ea/joph2021-6654604.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4cd7/8062195/6c5aee7649d3/joph2021-6654604.002.jpg

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本文引用的文献

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Retina. 2020 Aug;40(8):1500-1511. doi: 10.1097/IAE.0000000000002627.
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FOVEA-SPARING VERSUS COMPLETE INTERNAL LIMITING MEMBRANE PEELING IN VITRECTOMY FOR THE TREATMENT OF MACULAR HOLES.保留中心凹的内界膜剥除与完全内界膜剥除在玻璃体切割治疗黄斑裂孔中的比较。
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PEELING OF THE INTERNAL LIMITING MEMBRANE WITH FOVEAL SPARING FOR TREATMENT OF DEGENERATIVE LAMELLAR MACULAR HOLE.
内界膜剥离联合黄斑中心凹避开治疗退行性板层黄斑裂孔。
Retina. 2020 Jun;40(6):1087-1093. doi: 10.1097/IAE.0000000000002559.
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EPIRETINAL MEMBRANE REMOVAL WITH FOVEAL-SPARING INTERNAL LIMITING MEMBRANE PEELING: A Pilot Study.内界膜剥除联合黄斑区保留的内界膜撕除:一项初步研究。
Retina. 2019 Nov;39(11):2116-2124. doi: 10.1097/IAE.0000000000002274.
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Differential association of elevated inflammatory cytokines with postoperative fibrous proliferation and neovascularization after unsuccessful vitrectomy in eyes with proliferative diabetic retinopathy.增殖性糖尿病视网膜病变患者玻璃体切割术失败后,炎症细胞因子升高与术后纤维增生和新生血管形成的差异关联。
Clin Ophthalmol. 2017 Sep 19;11:1697-1705. doi: 10.2147/OPTH.S141821. eCollection 2017.
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Retina. 2014 Sep;34(9):1833-40. doi: 10.1097/IAE.0000000000000149.
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Graefes Arch Clin Exp Ophthalmol. 2014 Oct;252(10):1553-60. doi: 10.1007/s00417-014-2613-7. Epub 2014 Mar 23.
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