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肥胖的非酒精性脂肪性肝病印度患者生活方式相关行为的差异

Variation in Lifestyle-Related Behavior Among Obese Indian Patients With Non-alcoholic Fatty Liver Disease.

作者信息

Arora Charu, Malhotra Anita, Ranjan Piyush, Vikram Naval K, Dwivedi S N, Singh Namrata, Singh Vishwajeet

机构信息

Department of Home Science, University of Delhi, New Delhi, India.

Department of Home Science, Lakshmibai College, University of Delhi, New Delhi, India.

出版信息

Front Nutr. 2021 Apr 14;8:655032. doi: 10.3389/fnut.2021.655032. eCollection 2021.

Abstract

Lifestyle modification is the mainstay of treatment in Non-Alcoholic Fatty Liver Disease (NAFLD). Published Indian data on the diet and lifestyle of Indian NAFLD patients is scarce. This study explored variation in lifestyle-related behavior among obese patients with NAFLD. Ultrasonography (USG) diagnosed obese NAFLD patients ( = 140) were assessed for dietary intake [1-day 24 hours recall, food-frequency questionnaire (FFQ)] and physical activity (PA) [Global Physical Activity Questionnaire (GPAQ)]. Diet quality score (0-30) and physical activity (PA) levels were used to study variation in lifestyle and assess the effect of lifestyle on the severity of NAFLD. Compared to the recommendation, calorie consumption was 25.2% higher in nearly half (53.6%) of the subjects and mean macronutrient intake was imbalanced (60.3% carbohydrates, 12.4% protein, 25.5% fats). Variation was seen in terms of diet quality-good (3%), moderate (54.3%), or poor (43.5%) and intensity of PA-high (15%), moderate (47.9%), or low (37.1%). No patient had a combination of high PA and good diet quality within all grades of NAFLD. Our study suggests wide variation in lifestyles of obese patients with NAFLD and need for a more flexible and individualized modification of their diet and PA.

摘要

生活方式的改变是治疗非酒精性脂肪性肝病(NAFLD)的主要方法。关于印度NAFLD患者饮食和生活方式的已发表数据很少。本研究探讨了肥胖NAFLD患者与生活方式相关行为的差异。对经超声检查(USG)诊断的肥胖NAFLD患者(n = 140)进行饮食摄入评估[1天24小时回顾法、食物频率问卷(FFQ)]和身体活动(PA)评估[全球身体活动问卷(GPAQ)]。饮食质量评分(0 - 30)和身体活动(PA)水平用于研究生活方式的差异,并评估生活方式对NAFLD严重程度的影响。与建议值相比,近一半(53.6%)的受试者热量消耗高出25.2%,平均宏量营养素摄入不均衡(碳水化合物60.3%、蛋白质12.4%、脂肪25.5%)。在饮食质量方面存在差异——良好(3%)、中等(54.3%)或较差(43.5%),以及身体活动强度方面存在差异——高强度(15%)、中等强度(47.9%)或低强度(37.1%)。在所有NAFLD分级中,没有患者同时具备高强度身体活动和良好的饮食质量。我们的研究表明,肥胖NAFLD患者的生活方式存在很大差异,需要对他们的饮食和身体活动进行更灵活、个性化的调整。

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