Department of General Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, China.
Department of Nutrition and Food Hygiene, Public Health College, Harbin Medical University, Harbin, Heilongjiang Province, China.
J Gastroenterol Hepatol. 2019 Jan;34(1):256-262. doi: 10.1111/jgh.14360. Epub 2018 Jul 16.
Non-alcoholic fatty liver disease (NAFLD) is a multifactorial disease that involves a complex interaction between genetics, diet, and lifestyle. Although closely related with obese subjects, it is also common in lean humans. This study aimed to characterize the diet and lifestyle of lean and obese NAFLD patients in China.
To characterize the diet and lifestyle of lean and obese NAFLD patients, we conducted a matched case-control study that included 351 Chinese adults. General characteristics, dietary intake, and lifestyle were gathered by using a valid and reliable dietary questionnaire. We compared the dietary intake and lifestyle between lean and obese NAFLD patients.
All NAFLD patients had more total caloric, calorigenic nutrients (carbohydrate, fat, and protein), grain, potato, fruit, and iron with higher levels of waist circumference and overtime work but shorter sleep duration than their corresponding controls. Particularly, lean NAFLD patients consumed comparable total caloric, calorigenic nutrients, iron, sleep duration, and overtime work as obese NAFLD patients, though they consumed lower levels of grain, potato, and fruit (lean NAFLD patients vs. obese NAFLD patients: mean ± SD, g/day grain: 291.8 ± 83.8, 365.2 ± 89.0; potato: 63.5 ± 33.1, 80.4 ± 37.6; fruit: 324.3 ± 148.4, 414.0 ± 220.4; P < 0.0001).
Non-alcoholic fatty liver disease patients had higher total caloric, calorigenic nutrients, grain, potato, fruit, iron, and overtime work but shorter sleep duration. Lean NAFLD patients had comparable total caloric, calorigenic nutrients, iron, sleep duration, and overtime work as obese NAFLD patients. These features could be used to the nutritional education and therapeutic guidance for lean NAFLD patients in the future.
非酒精性脂肪性肝病（NAFLD）是一种多因素疾病，涉及遗传、饮食和生活方式之间的复杂相互作用。尽管它与肥胖者密切相关，但在瘦人中也很常见。本研究旨在描述中国瘦型和肥胖型 NAFLD 患者的饮食和生活方式。
为了描述瘦型和肥胖型 NAFLD 患者的饮食和生活方式，我们进行了一项匹配病例对照研究，纳入了 351 名中国成年人。通过使用有效和可靠的饮食问卷收集一般特征、饮食摄入和生活方式。我们比较了瘦型和肥胖型 NAFLD 患者的饮食摄入和生活方式。
所有 NAFLD 患者的总热量、产热营养素（碳水化合物、脂肪和蛋白质）、谷物、土豆、水果和铁的摄入量均较高，腰围和加班时间较长，但睡眠时间较短。特别是，瘦型 NAFLD 患者的总热量、产热营养素、铁、睡眠时间和加班时间与肥胖型 NAFLD 患者相当，尽管他们的谷物、土豆和水果摄入量较低（瘦型 NAFLD 患者与肥胖型 NAFLD 患者相比：平均值 ± 标准差，g/天谷物：291.8 ± 83.8，365.2 ± 89.0；土豆：63.5 ± 33.1，80.4 ± 37.6；水果：324.3 ± 148.4，414.0 ± 220.4；P < 0.0001）。
非酒精性脂肪性肝病患者的总热量、产热营养素、谷物、土豆、水果、铁和加班时间较高，但睡眠时间较短。瘦型 NAFLD 患者的总热量、产热营养素、铁、睡眠时间和加班时间与肥胖型 NAFLD 患者相当。这些特征可用于未来对瘦型 NAFLD 患者的营养教育和治疗指导。
