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多发伤:基础科学与临床证据的最新进展

Polytrauma: update on basic science and clinical evidence.

作者信息

Nauth Aaron, Hildebrand Frank, Vallier Heather, Moore Timothy, Leenen Luke, Mckinley Todd, Pape Hans-Christoph

机构信息

Division of Orthopaedics, Department of Surgery, University of Toronto and St. Michael's Hospital, Toronto, Ontario, Canada.

Department of Trauma and Reconstructive Surgery, University Hospital RWTH Aachen. Aachen, Germany.

出版信息

OTA Int. 2021 Feb 23;4(1):e116. doi: 10.1097/OI9.0000000000000116. eCollection 2021 Mar.

DOI:10.1097/OI9.0000000000000116
PMID:33937720
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8016602/
Abstract

The management of multiply injured or severely injured patients is a complex and dynamic process. Timely and safe fracture fixation is a critical component of the multidisciplinary care that these patients require. Effective management of these patients, and their orthopaedic injuries, requires a strong understanding of the pathophysiology of the response to trauma and indicators of patient status, as well as an appreciation for the dynamic nature of these parameters. Substantial progress in both clinical and basic science research in this area has advanced our understanding of these concepts and our approach to management of the polytraumatized patient. This article summarizes a symposium on this topic that was presented by an international panel of experts at the 2020 Virtual Annual Meeting of the Orthopaedic Trauma Association.

摘要

对多发伤或重伤患者的管理是一个复杂且动态的过程。及时且安全地固定骨折是这些患者所需多学科护理的关键组成部分。对这些患者及其骨科损伤进行有效管理,需要深入了解创伤反应的病理生理学和患者状态指标,以及认识到这些参数的动态性质。该领域临床和基础科学研究的重大进展增进了我们对这些概念的理解以及对多发伤患者的管理方法。本文总结了由国际专家小组在2020年骨科创伤协会虚拟年会上举办的关于该主题的研讨会内容。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc9c/8016602/3029e4ddf85f/oi9-4-e116-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc9c/8016602/0815f9a1ddfc/oi9-4-e116-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc9c/8016602/3029e4ddf85f/oi9-4-e116-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc9c/8016602/0815f9a1ddfc/oi9-4-e116-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc9c/8016602/3029e4ddf85f/oi9-4-e116-g002.jpg

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J Trauma Acute Care Surg. 2021 Mar 1;90(3):441-450. doi: 10.1097/TA.0000000000002998.
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Protective effects of new femoral reaming techniques (Reamer irrigator aspirator, RIA I and II) on pulmonary function and posttraumatic contusion (CT morphology) - results from a standardized large animal model.新型股骨扩髓技术(扩髓冲洗吸引器,RIA I 和 II)对肺功能和创伤后挫伤(CT 形态)的保护作用-来自标准化大动物模型的结果。
Injury. 2021 Jan;52(1):26-31. doi: 10.1016/j.injury.2020.10.027. Epub 2020 Oct 6.
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Eur J Med Res. 2025 Apr 2;30(1):228. doi: 10.1186/s40001-025-02477-8.
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Translating Biomarker Research into Clinical Practice in Orthopaedic Trauma: A Systematic Review.将生物标志物研究转化为骨科创伤临床实践:一项系统综述。
J Clin Med. 2025 Feb 17;14(4):1329. doi: 10.3390/jcm14041329.
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