Zhou Zhi-Hao, Mao Jin, Cao Da
Department of Emergency Medicine, Zhongda Hospital Southeast University, Nanjing 210009, Jiangsu Province, China.
World J Psychiatry. 2025 Jul 19;15(7):105742. doi: 10.5498/wjp.v15.i7.105742.
Patients with multiple injuries endure not just physical trauma and suffering but are also at risk of psychological conditions such as posttraumatic stress disorder (PTSD), anxiety, and depression. The co-occurrence of PTSD in these patients may cause prolonged physical and mental health complications, thereby further increasing their healthcare expenses.
To determine the association between the high-risk factors of PTSD and anxiety as well as depression among patients with multiple injuries.
This study selected 110 patients with multiple injuries who were admitted to our hospital from November 2022 to November 2024. The number and percentage of patients developing PTSD were tallied. Univariate and multivariate analyses were conducted to investigate the high-risk factors of PTSD in these patients. Subsequently, the associations between these factors and the anxiety and depression levels of patients were analyzed.
Of the 110 patients, 33 suffered from PTSD, representing an incidence rate of 30.0%. The univariate analysis identified age, personality, Hamilton Anxiety Scale (HAMA), Hamilton Depression Scale (HAMD), economic status, negative life events, and smoking history to be significantly associated with PTSD in patients with multiple injuries. Further, the multivariate analysis revealed age, HAMA, HAMD, monthly income, and negative life events as prominent high-risk factors for PTSD in such patients. Regarding the relationships between these factors and HAMA and HAMD, age exhibited a significant positive correlation ( = 0.398, < 0.001; = 0.387, < 0.001), monthly income showed a significant negative correlation ( = -0.437, < 0.001; = -0.319, < 0.001), and negative life events demonstrated a significant positive correlation ( = 0.505, < 0.001; = 0.365, < 0.001).
These results indicate age, HAMA, HAMD, monthly income, negative life events, as high-risk factors for PTSD in patients with multiple injuries, among which age, monthly income, and negative life events are closely associated with anxiety and depression.
多发伤患者不仅承受身体创伤和痛苦，还面临创伤后应激障碍（PTSD）、焦虑和抑郁等心理问题的风险。这些患者中PTSD的共病可能导致长期的身心健康并发症，从而进一步增加他们的医疗费用。
确定多发伤患者中PTSD与焦虑以及抑郁的高危因素之间的关联。
本研究选取了2022年11月至2024年11月期间我院收治的110例多发伤患者。统计发生PTSD的患者数量及百分比。进行单因素和多因素分析以探究这些患者中PTSD的高危因素。随后，分析这些因素与患者焦虑和抑郁水平之间的关联。
110例患者中，33例患有PTSD，发病率为30.0%。单因素分析确定年龄、性格、汉密尔顿焦虑量表（HAMA）、汉密尔顿抑郁量表（HAMD）、经济状况、负性生活事件和吸烟史与多发伤患者的PTSD显著相关。此外，多因素分析显示年龄、HAMA、HAMD、月收入和负性生活事件是此类患者PTSD的突出高危因素。关于这些因素与HAMA和HAMD之间的关系，年龄呈显著正相关（r = 0.398，P < 0.001；r = 0.387，P < 0.001），月收入呈显著负相关（r = -0.437，P < 0.001；r = -0.319，P < 0.001），负性生活事件呈显著正相关（r = 0.505，P < 0.001；r = 0.365，P < 0.001）。
这些结果表明年龄、HAMA、HAMD、月收入、负性生活事件是多发伤患者PTSD的高危因素，其中年龄、月收入和负性生活事件与焦虑和抑郁密切相关。
