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本文引用的文献

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ACOG Practice Bulletin No. 190: Gestational Diabetes Mellitus.美国妇产科医师学会临床实践通告第 190 号:妊娠期糖尿病。
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2
Is primiparity a risk factor for advanced maternal age pregnancies?初产是高龄孕产妇妊娠的一个风险因素吗?
J Matern Fetal Neonatal Med. 2017 Jun;30(11):1283-1287. doi: 10.1080/14767058.2016.1211633. Epub 2016 Aug 2.
3
Effect of maternal age on pregnancy outcome and cesarean delivery rate.产妇年龄对妊娠结局及剖宫产率的影响。
J Clin Med Res. 2015 Feb;7(2):97-102. doi: 10.14740/jocmr1904w. Epub 2014 Nov 19.
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The impact of parity on perinatal outcomes in pregnancies complicated by advanced maternal age.产次对高龄孕产妇妊娠围产期结局的影响。
J Turk Ger Gynecol Assoc. 2013 Dec 1;14(4):205-9. doi: 10.5152/jtgga.2013.62347. eCollection 2013.
5
Pregnancy outcome at advanced maternal age in a group of African women in two teaching Hospitals in Yaounde, Cameroon.喀麦隆雅温得两所教学医院中一组非洲女性高龄孕产妇的妊娠结局
Pan Afr Med J. 2013 Apr 7;14:134. doi: 10.11604/pamj.2013.14.134.2315. Print 2013.
6
Advanced maternal age and obstetric morbidity for women giving birth in Victoria, Australia: A population-based study.澳大利亚维多利亚州高龄产妇与产科发病率:一项基于人群的研究。
Aust N Z J Obstet Gynaecol. 2012 Jun;52(3):229-34. doi: 10.1111/j.1479-828X.2012.01427.x. Epub 2012 Apr 13.
7
Pregnancy outcome in late maternal age in a high-income developing country.高收入发展中国家高龄产妇的妊娠结局。
Arch Gynecol Obstet. 2011 Nov;284(5):1113-6. doi: 10.1007/s00404-010-1821-6. Epub 2010 Dec 28.
8
Pregnancy outcome at extremely advanced maternal age.极高龄产妇的妊娠结局。
Am J Obstet Gynecol. 2010 Dec;203(6):558.e1-7. doi: 10.1016/j.ajog.2010.07.039. Epub 2010 Oct 20.
9
Advanced maternal age and the risk of cesarean birth: a systematic review.高龄产妇与剖宫产分娩风险:系统评价。
Birth. 2010 Sep;37(3):219-26. doi: 10.1111/j.1523-536X.2010.00409.x.
10
The impact of advanced maternal age and parity on obstetric and perinatal outcomes in singleton gestations.高龄产妇和多胎妊娠对单胎妊娠的产科和围产结局的影响。
Arch Gynecol Obstet. 2011 Jul;284(1):31-7. doi: 10.1007/s00404-010-1587-x. Epub 2010 Jul 15.

初产妇比例对 40 岁以上孕妇产科及围生期结局的影响:一项回顾性研究。

The effect of parity on obstetric and perinatal outcomes in pregnancies at the age of 40 and above: a retrospective study.

机构信息

Simten Genc, Obstetrics and Gynecology Department, Okmeydani Training and Research Hospital, Istanbul 34384, Turkey,

出版信息

Croat Med J. 2021 Apr 30;62(2):130-136. doi: 10.3325/cmj.2021.62.130.

DOI:10.3325/cmj.2021.62.130
PMID:33938652
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8107994/
Abstract

AIM

To examine the characteristics of pregnancies at a very advanced maternal age and the effect of parity on adverse obstetric outcomes.

METHODS

We retrospectively reviewed the records of women who gave birth at the Obstetrics and Gynecology Department of Okmeydanı Training and Research Hospital between January 2012 and December 2019. Overall, 22 448 of women were younger than 40 and 593 were aged 40 and older. Women aged 40 and older were divided into the primiparous (52 or 8.77%) and multiparous group (541 or 91.23%).

RESULTS

Significantly more women aged 40 and older had a cesarean section. The most common indications for a secondary cesarean delivery in both age groups were a previous cesarean procedure or uterine operation. The most frequent indication for primary cesarean section in both groups was fetal distress. Cesarean section rates due to non-progressive labor, fetal distress, and preeclampsia were significantly more frequent in primiparous women compared with multiparous women aged 40 and older. In primiparous women, fetal birth weight was lower and preeclampsia/gestational hypertension frequency were higher.

CONCLUSION

Since primiparity was a risk factor for lower fetal birth weight and preeclampsia/gestational hypertension in the age group of 40 years and above, more attention should be paid to the follow-up and treatment of these patients.

摘要

目的

探讨极高龄产妇妊娠的特点及初产妇与经产妇对不良产科结局的影响。

方法

我们回顾性分析了 2012 年 1 月至 2019 年 12 月在 Okmeydanı培训和研究医院妇产科分娩的妇女的记录。共有 22448 名年龄小于 40 岁的妇女和 593 名年龄 40 岁及以上的妇女。年龄在 40 岁及以上的妇女分为初产妇(52 例,8.77%)和经产妇组(541 例,91.23%)。

结果

年龄在 40 岁及以上的妇女剖宫产率显著升高。两组剖宫产的主要指征均为既往剖宫产史或子宫手术史。两组中初产妇行剖宫产的主要指征均为胎儿窘迫。初产妇因产程无进展、胎儿窘迫和子痫前期行剖宫产的比例明显高于经产妇。初产妇的胎儿出生体重较低,子痫前期/妊娠期高血压的发生率较高。

结论

由于初产是年龄在 40 岁及以上的产妇胎儿出生体重低和子痫前期/妊娠期高血压的危险因素,因此应更加关注这些患者的随访和治疗。