Department of Pediatrics, Clinical Hospital Center Rijeka, Rijeka, Croatia.
Department of Emergency Medicine, Clinical Hospital Center Rijeka, Rijeka, Croatia.
J Pediatr Endocrinol Metab. 2021 May 3;34(8):1045-1048. doi: 10.1515/jpem-2020-0720. Print 2021 Aug 26.
Hyperglycemic hyperosmolar state (HHS) is one of the most severe acute complications of diabetes mellitus (DM) characterized by severe hyperglycemia and hyperosmolality without significant ketosis and acidosis. What is new? Since HHS in the pediatric population is rare and potentially life-threatening, every reported case is very valuable for raising awareness among healthcare professionals.
A 7-year-old boy with previously diagnosed Joubert syndrome was admitted due to vomiting, polydipsia and polyuria started several days earlier. He was severely dehydrated, and the initial blood glucose level was 115 mmol/L. Based on clinical manifestations and laboratory results, he was diagnosed with T1DM and HHS. The treatment with intravenous fluid was started and insulin administration began later. He was discharged after 10 days without any complications related to HHS.
Since HHS has a high mortality rate, early recognition, and proper management are necessary for a better outcome.
高血糖高渗状态(HHS)是糖尿病(DM)最严重的急性并发症之一,其特征为严重高血糖和高渗性,而无显著酮症和酸中毒。有何新内容?由于儿科人群中的 HHS 较为罕见且可能危及生命,因此每例报告的病例对于提高医护人员的认识都非常有价值。
一名 7 岁男孩,此前被诊断为杰特综合征,因数天前开始出现呕吐、多饮和多尿而入院。他存在严重脱水,初始血糖水平为 115mmol/L。根据临床表现和实验室结果,他被诊断为 1 型糖尿病和 HHS。开始给予静脉补液治疗,随后开始给予胰岛素治疗。他在 10 天后出院,没有出现与 HHS 相关的任何并发症。
由于 HHS 的死亡率较高,因此早期识别和适当的治疗对于获得更好的结局至关重要。