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广泛的个体呼吸顺应性弥散很可能证实了不同的呼吸力学。

Broad individual immersion-scattering of respiratory compliance likely substantiates dissimilar breathing mechanics.

机构信息

Underwater Research Team (ERRSO), Military Biomedical Research Institute-IRBA, BP 600, 83800, Toulon Cedex 9, France.

Laboratoire Motricité Humaine Expertise Sport Santé (LAMHESS, UPR6312), Nice, France.

出版信息

Sci Rep. 2021 May 3;11(1):9434. doi: 10.1038/s41598-021-88925-x.

Abstract

Head-out water immersion alters respiratory compliance which underpins defining pressure at a "Lung centroid" and the breathing "Static Lung Load". In diving medicine as in designing dive-breathing devices a single value of lung centroid pressure is presumed as everyone's standard. On the contrary, we considered that immersed respiratory compliance is disparate among a homogenous adult group (young, healthy, sporty). We wanted to substantiate this ample scattering for two reasons: (i) it may question the European standard used in designing dive-breathing devices; (ii) it may contribute to understand the diverse individual figures of immersed work of breathing. Resting spirometric measurements of lung volumes and the pressure-volume curve of the respiratory system were assessed for 18 subjects in two body positions (upright Up, and supine Sup). Measurements were taken in air (Air) and with subjects immersed up to the sternal notch (Imm). Compliance of the respiratory system (Crs) was calculated from pressure-volume curves for each condition. A median 60.45% reduction in Crs was recorded between Up-Air and Up-Imm (1.68 vs 0.66 L/kPa), with individual reductions ranging from 16.8 to 82.7%. We hypothesize that the previously disregarded scattering of immersion-reduced respiratory compliance might participate to substantial differences in immersed work of breathing.

摘要

头高脚低位浸水会改变呼吸顺应性,从而影响“肺质心”压力和呼吸“静态肺负荷”的定义。在潜水医学中,就像设计潜水呼吸设备一样,假定每个人的肺质心压力值都是标准值。相反,我们认为在一个同质的成年人群体中(年轻、健康、运动),浸入式呼吸顺应性存在差异。我们之所以要证实这一点,有两个原因:(i)它可能会对设计潜水呼吸设备所使用的欧洲标准提出质疑;(ii)它可能有助于理解不同个体的呼吸浸入工作量。对 18 名受试者在两种体位(直立位 Up 和仰卧位 Sup)下进行了肺容量和呼吸系统压力-容积曲线的静息肺功能测量。测量分别在空气(Air)和受试者浸入胸骨切迹(Imm)的情况下进行。每个条件下的呼吸系统顺应性(Crs)均根据压力-容积曲线计算。与 Up-Air 相比,Up-Imm 时 Crs 中位数降低了 60.45%(1.68 比 0.66 L/kPa),个体降低幅度为 16.8%至 82.7%。我们假设,先前被忽视的浸入式呼吸顺应性降低的分散性可能会导致浸入式呼吸工作量的显著差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fa2/8093428/c45bb4d6f5ef/41598_2021_88925_Fig1_HTML.jpg

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