University of Liverpool, Liverpool, UK.
Malawi-Liverpool-Wellcome Trust Clinical Research Programme, College of Medicine, University of Malawi, Blantyre, Malawi.
Microb Genom. 2021 May;7(5). doi: 10.1099/mgen.0.000532.
Increasing antimicrobial resistance and limited alternative treatments have led to fluoroquinolone-resistant strain inclusion on the WHO global priority pathogens list. In this study we characterized multiple isolates from Malawi with whole genome sequence analysis, identifying the acquirable fluoroquinolone resistance determinant .
抗微生物药物耐药性的增加和有限的替代治疗方法导致氟喹诺酮类耐药菌株被列入世卫组织全球优先病原体名单。在这项研究中,我们通过全基因组序列分析对来自马拉维的多个分离株进行了特征描述,确定了可获得的氟喹诺酮类耐药决定因素。