基于家庭的体育活动干预对自身免疫性风湿病患者的疗效：系统评价和荟萃分析。
Efficacy of home-based physical activity interventions in patients with autoimmune rheumatic diseases: A systematic review and meta-analysis.
机构信息
Applied Physiology & Nutrition Research Group, School of Physical Education and Sport, Rheumatology Division, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, SP, Brazil. Laboratory of Assessment and Conditioning in Rhematology, Faculdade de Medicina FMUSP, Disciplina de Reumatologia, Universidade de Sao Paulo, Sao Paulo, SP, Brazil Av. Dr. Arnaldo, 455, ZIP code: 01246-903, Sao Paulo-SP, Brazil; Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
Applied Physiology & Nutrition Research Group, School of Physical Education and Sport, Rheumatology Division, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, SP, Brazil. Laboratory of Assessment and Conditioning in Rhematology, Faculdade de Medicina FMUSP, Disciplina de Reumatologia, Universidade de Sao Paulo, Sao Paulo, SP, Brazil Av. Dr. Arnaldo, 455, ZIP code: 01246-903, Sao Paulo-SP, Brazil; Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
出版信息
Semin Arthritis Rheum. 2021 Jun;51(3):576-587. doi: 10.1016/j.semarthrit.2021.04.004. Epub 2021 Apr 16.
INTRODUCTION
Physical activity (PA) has been receiving increasing interest in recent years as an adjuvant therapy for autoimmune rheumatic disease (ARDs), but there is scarce information about the efficacy of home-based PA for patients with ARDs.
OBJECTIVE
To perform a systematic review and meta-analysis on the efficacy of home-based physical activity (PA) interventions in improving health-related quality of life, functional capacity, pain, and disease activity in patients with ARDs.
METHODS
Searches were performed in PubMed, Web of Science, Scopus, Cochrane, CINAHL database and Sport Discus. Trials were considered eligible if they included a home-based physical activity intervention. The population included adults with autoimmune rheumatic diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus, idiopathic inflammatory myopathies, systemic sclerosis and ankylosing spondylitis), comparisons included non-physical activity control or centre-based interventions (i.e., interventions performed on a specialized exercise centre) and the outcomes were quality of life, pain, functional capacity, disease activity and inflammation.
RESULTS
Home-based physical activity improved quality of life (p<0.01; g = 0.69; IC95%, 0.61 to 1.07) and functional capacity (p = 0.04; g = - 0.51; IC95%, -0.86; -0.16), and reduced disease activity (p = 0.03; g = - 0.60; IC95%, -1.16; -0.04) and pain (p = 0.01; g = -1.62; IC95%, -2.94 to -0.31) compared to the non-physical activity control condition. Additionally, home-based physical activity interventions were as effective as centre-based interventions for all investigated outcomes.
CONCLUSION
Home-based PA is an efficacious strategy to improve disease control and aleviate symptoms in ARD.
简介
近年来，体力活动（PA）作为自身免疫性风湿病（ARDs）的辅助治疗方法越来越受到关注，但关于 ARD 患者家庭 PA 的疗效信息却很少。
目的
对家庭体力活动（PA）干预改善 ARD 患者健康相关生活质量、功能能力、疼痛和疾病活动的疗效进行系统评价和荟萃分析。
方法
在 PubMed、Web of Science、Scopus、Cochrane、CINAHL 数据库和 Sport Discus 中进行检索。如果研究包含家庭体力活动干预，则认为其符合纳入标准。研究人群为患有自身免疫性风湿病的成年人（例如类风湿关节炎、系统性红斑狼疮、特发性炎性肌病、系统性硬化症和强直性脊柱炎），比较组包括非体力活动对照组或中心基础干预组（即在专门的运动中心进行的干预），结局指标为生活质量、疼痛、功能能力、疾病活动和炎症。
结果
家庭体力活动改善了生活质量（p<0.01；g=0.69；95%CI，0.61 至 1.07）和功能能力（p=0.04；g=-0.51；95%CI，-0.86；-0.16），降低了疾病活动（p=0.03；g=-0.60；95%CI，-1.16；-0.04）和疼痛（p=0.01；g=-1.62；95%CI，-2.94；-0.31），与非体力活动对照组相比。此外，家庭体力活动干预与中心基础干预对所有研究结局均具有相同的疗效。
结论
家庭 PA 是改善 ARD 疾病控制和缓解症状的有效策略。
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