Bobrek Kamila, Sokół Ireneusz, Gaweł Andrzej
Department of Epizootiology and Clinic of Bird and Exotic Animals, Wroclaw University of Environmental and Life Sciences, 50-366 Wrocław, Poland.
Private Veterinary Service, SM-ARTVET, 51-361 Wrocław, Poland.
Pathogens. 2021 Apr 30;10(5):538. doi: 10.3390/pathogens10050538.
The microbiota of the gastrointestinal tract of humans and animals is inhabited by a diverse community of bacteria, fungi, protozoa, and viruses. In cases where there is an imbalance in the normal microflora or an immunosuppression on the part of the host, these opportunistic microorganisms can cause severe infections. The study presented here evaluates the biochemical and antifungal susceptibility features of spp., uncommon non- strains isolated from the gastrointestinal tract of healthy turkeys. The and accounted for 7.7% of all fungi isolates. The biochemical tests showed that had active esterase (C4), esterase-lipase (C8) valine arylamidase, naphthol-AS-BI phosphohydrolase, α-galactosidase, and β-glucosidase. Likewise, demonstrated esterase-lipase (C8), lipase (C14), valine arylamidase, naphthol-AS-BI phosphohydrolase, α-galactosidase, and β-glucosidase activity. and isolated from turkeys were itraconazole resistant and amphotericin B, fluconazole, and voriconazole susceptible. Compared with human isolates, the MIC range and MIC values of turkey isolates to itraconazole were in a higher range limit in both species, while MIC values to amphotericin B, fluconazole, and voriconazole were in a lower range limit. Furthermore, the obtained ITS1-5.8rRNA-ITS2 fragment sequences were identical with and sequences isolated from humans indicating that these isolates are shared pathogens.
人和动物胃肠道的微生物群由细菌、真菌、原生动物和病毒等多种群落组成。在正常微生物群失衡或宿主出现免疫抑制的情况下，这些机会性微生物可导致严重感染。本文所呈现的研究评估了从健康火鸡胃肠道分离出的罕见非菌株的生化特性和抗真菌药敏特性。和占所有真菌分离株的7.7%。生化试验表明，具有活性酯酶（C4）、酯酶 - 脂肪酶（C8）、缬氨酸芳基酰胺酶、萘酚 - AS - BI磷酸水解酶、α - 半乳糖苷酶和β - 葡萄糖苷酶。同样，也表现出酯酶 - 脂肪酶（C8）、脂肪酶（C14）、缬氨酸芳基酰胺酶、萘酚 - AS - BI磷酸水解酶、α - 半乳糖苷酶和β - 葡萄糖苷酶活性。从火鸡中分离出的和对伊曲康唑耐药，对两性霉素B、氟康唑和伏立康唑敏感。与人类分离株相比，火鸡分离株对伊曲康唑的MIC范围和MIC值在两个物种中均处于较高范围界限，而对两性霉素B、氟康唑和伏立康唑的MIC值处于较低范围界限。此外，所获得的ITS1 - 5.8rRNA - ITS2片段序列与从人类分离出的和序列相同，表明这些分离株是共同病原体。
