Listinsky C M
University of Rochester School of Medicine and Dentistry, New York.
Am J Clin Pathol. 1988 Aug;90(2):189-92. doi: 10.1093/ajcp/90.2.189.
Erythrophagocytosis by histiocytes in the sinuses of axillary lymph nodes is a common yet little-known phenomenon. The axillary lymph node dissections of 23 patients were studied by light microscopy and graded for the amount of erythrophagocytosis. None of the patients had evidence of a systemic hemolytic process. Nineteen of them exhibited some degree of erythrophagocytosis, and this was present even in four of the six patients who never had a prior breast biopsy. Breast biopsy was associated with massive degrees of erythrophagocytosis in 8 of 17 patients, and after a postbiopsy interval of two weeks 11 of 13 patients had hemosiderin deposition in the lymph nodes, evidence of red blood cell breakdown. This study serves to substantiate statements, made by others without confirmatory data, that large degrees of erythrophagocytosis may be seen in axillary lymph nodes after breast biopsies and that small amounts of erythrophagocytosis may be identified in lymph nodes of patients with no prior trauma history.
腋窝淋巴结窦内组织细胞的红细胞吞噬现象常见但鲜为人知。对23例患者的腋窝淋巴结清扫标本进行光学显微镜检查，并根据红细胞吞噬量进行分级。所有患者均无全身性溶血过程的证据。其中19例表现出一定程度的红细胞吞噬现象，甚至在6例从未接受过乳腺活检的患者中有4例也存在此现象。乳腺活检与17例患者中的8例出现大量红细胞吞噬现象有关，活检后两周时，13例患者中有11例淋巴结出现含铁血黄素沉积，这是红细胞分解的证据。这项研究证实了其他人在没有确凿数据的情况下所做的陈述，即乳腺活检后腋窝淋巴结中可能会出现大量红细胞吞噬现象，并且在没有既往创伤史的患者的淋巴结中可能会发现少量红细胞吞噬现象。
