Departments of Oral and Maxillofacial Surgery, Queen Alexandra Hospital, Portsmouth, PO6 3LY, UK.
Departments of Clinical Radiology, Queen Alexandra Hospital, Portsmouth, PO6 3LY, UK.
Br J Oral Maxillofac Surg. 2021 Jul;59(6):720-721. doi: 10.1016/j.bjoms.2021.04.008. Epub 2021 Apr 21.
The UK COVID vaccination programme has progressed at an astonishing rate since the first patients received their doses in December 2020. It is well known that other vaccines including influenza and human papilloma virus (HPV) can result in reactive lymphadenopathy in the axilla and/or neck. Patients are now presenting via the two week wait neck lump clinic with supraclavicular fossa and low neck lymphadenopathy related to COVID vaccination, and to similar one stop breast clinics with axillary lymph nodes. In an audit of 80 patients seen over a period of one month, we found COVID vaccine-related low neck lymphadenopathy in four cases (5%), with an additional rectal cancer patient thought to have metastatic disease who presented with a Virchow type node. COVID vaccine-related lymphadenopathy should be considered in the differential diagnosis of low-neck nodes if they occurred shortly after vaccination, but it is important to exclude sinister disease using ultrasound and other investigations as necessary.
自 2020 年 12 月首批患者接种疫苗以来，英国 COVID 疫苗接种计划进展迅速。众所周知，包括流感和人乳头瘤病毒（HPV）在内的其他疫苗可导致腋窝和/或颈部反应性淋巴结病。现在，患者通过两周等待颈部肿块诊所出现与 COVID 疫苗接种相关的锁骨上窝和低位颈部淋巴结病，并出现类似的一站式乳房诊所的腋窝淋巴结病。在对一个月内就诊的 80 名患者进行的审计中，我们发现 4 例（5%）存在 COVID 疫苗相关的低位颈部淋巴结病，另一名患有直肠癌的患者被认为患有转移性疾病，表现为 Virchow 型淋巴结。如果在接种疫苗后不久发生低位颈部淋巴结，应考虑 COVID 疫苗相关的淋巴结病作为鉴别诊断，但重要的是使用超声和其他检查排除恶性疾病。
