钌（II）配合物作为用于针对三阴性乳腺癌细胞的肿瘤特异性光动力疗法的生物正交双光子光敏剂。
Ruthenium(II) complexes as bioorthogonal two-photon photosensitizers for tumour-specific photodynamic therapy against triple-negative breast cancer cells.
作者信息
Lin Mingwei, Zou Shanshan, Liao Xinxing, Chen Yu, Luo Diqing, Ji Liangnian, Chao Hui
机构信息
MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, P. R. China.
Department of Dermatology, The Eastern Division of the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510275, P. R. China.
出版信息
Chem Commun (Camb). 2021 May 4;57(36):4408-4411. doi: 10.1039/d1cc00661d.
PMID:33949487
Abstract
Herein, we developed the first Ru(ii) complex-based bioorthogonal two-photon photosensitizers. Through bioorthogonal labelling, they realize effective tumour-specific photodynamic therapy against triple-negative breast cancer cells.
摘要
在此，我们开发了首个基于钌（II）配合物的生物正交双光子光敏剂。通过生物正交标记，它们实现了针对三阴性乳腺癌细胞的有效肿瘤特异性光动力疗法。
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