Fundação Oswaldo Cruz (FIOCRUZ/MG), Instituto René Rachou, Avenida Augusto de Lima, 1715, Barro Preto, 30180-104 Belo Horizonte, MG, Brazil.
An Acad Bras Cienc. 2021 Apr 30;93(3):e20200254. doi: 10.1590/0001-37652021XXXX. eCollection 2021.
Lutzomyia longipalpis is the most important vector of Leishmania infantum, the etiological agent of visceral leishmaniasis (VL) in the New World. It is a permissive vector susceptible to infection with several Leishmania species. One of the advantages that favors the study of this sand fly is the possibility of colonization in the laboratory. For this reason, several researchers around the world use this species as a model for different subjects including biology, insecticides testing, host-parasite interaction, physiology, genetics, proteomics, molecular biology, and saliva among others. In 2003, we published our first review (Soares & Turco 2003) on this vector covering several aspects of Lu. longipalpis. This current review summarizes what has been published between 2003-2020. During this period, modern approaches were incorporated following the development of more advanced and sensitive techniques to assess this sand fly.
长刺舌蝇是新域内脏利什曼原虫（引起内脏利什曼病的病原体）的最重要媒介，也是新世界中利什曼病的主要传播媒介。它是一种允许感染几种利什曼原虫的媒介。有利于研究这种沙蝇的一个优势是它在实验室中进行定殖的可能性。出于这个原因，世界各地的许多研究人员都将该物种作为生物学、杀虫剂测试、宿主-寄生虫相互作用、生理学、遗传学、蛋白质组学、分子生物学和唾液等不同主题的模型。2003 年，我们发表了第一篇关于该媒介的综述（Soares & Turco 2003），涵盖了 Lu. longipalpis 的几个方面。本综述总结了 2003 年至 2020 年期间发表的内容。在此期间，随着更先进和敏感技术的发展，采用了现代方法来评估这种沙蝇。
