Department of Oral Surgery, UNISAGRADO, Bauru, São Paulo, Brazil.
Department of Oral Implantology and Prosthesis, Universidade Federal of Uberlândia, Uberlândia, Brazil.
Br J Oral Maxillofac Surg. 2021 Jul;59(6):625-632. doi: 10.1016/j.bjoms.2020.08.050. Epub 2020 Aug 19.
This study was a systematic review with meta-analysis to evaluate the influence of hyperbaric oxygen therapy (HBOT) on the survival of dental implants placed in patients who had had radiotherapy for cancer of the head and neck. A systematic literature search was conducted using the PubMed/Medline, Science Direct, Embase and the Cochrane Library, between January 1985 and July 2018. The study observed the PRISMA (Preferred Reporting Items for Systematic review and Meta-Analysis) declaration and norms, and the systematic review was duly recorded in the PROSPERO (International prospective register of systematic reviews) database. Inclusion and exclusion criteria were applied, and all articles were selected on the basis of PICO questions. The process of eligibility and quality evaluation yielded three studies for statistical analysis. Based on the survival rates, there was no evidence that the risk of an implant failing was different between the patients who received HBOT and those who did not. Moreover, the risk of an implant failing did not depend on the anatomical site. HBOT exerted no beneficial influence on the survival rates of implants placed in irradiated patients, and the risk of an implant failing did not depend on its location.
本研究是一项系统评价和荟萃分析，旨在评估高压氧治疗（HBOT）对接受头颈部癌症放疗患者植入牙存活率的影响。使用 PubMed/Medline、Science Direct、Embase 和 Cochrane Library，从 1985 年 1 月至 2018 年 7 月进行了系统的文献检索。本研究观察了 PRISMA（系统评价和荟萃分析的首选报告项目）声明和规范，并在 PROSPERO（国际系统评价注册库）数据库中对系统评价进行了适当的记录。应用了纳入和排除标准，并根据 PICO 问题选择了所有文章。根据入选和质量评估的结果，有三项研究进行了统计学分析。基于存活率，没有证据表明接受 HBOT 的患者和未接受 HBOT 的患者之间的种植体失败风险有差异。此外，种植体失败的风险与解剖部位无关。HBOT 对接受放疗的患者植入物的存活率没有有益影响，并且种植体失败的风险与其位置无关。
