Department of Orthopaedic Surgery, Faculty of Medicine, Fukuoka University, Fukuoka, Japan;
Department of Orthopaedic Surgery, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.
Anticancer Res. 2021 May;41(5):2211-2215. doi: 10.21873/anticanres.14997.
Elastofibroma dorsi is an uncommon benign fibroblastic pseudotumor that typically occurs in the subscapular region of middle-aged or older individuals. The pathogenesis is still unclear and a matter of debate. Magnetic resonance imaging can be used as a first-line investigation of the lesion and reveals a lenticular soft-tissue mass with a signal intensity similar to that of skeletal muscle interlaced with strands of fat. Biopsy is not necessary if all pathognomonic criteria are present. A conservative "wait and see" attitude is reasonable and immediate surgery is no more the standard treatment of elastofibroma dorsi. This review provides an updated overview of the diagnosis, management and pathogenesis of elastofibroma dorsi. We also discuss recent advances in our understanding of genomic alterations in elastofibroma dorsi.
背阔肌纤维瘤是一种不常见的良性成纤维细胞假瘤，通常发生在中老年人群的肩胛下区域。其发病机制尚不清楚，存在争议。磁共振成像可作为病变的一线检查手段，显示出与骨骼肌交织的条纹状脂肪的透镜状软组织肿块，信号强度相似。如果存在所有特征性标准，则不需要进行活检。保守的“观望”态度是合理的，立即手术不再是背阔肌纤维瘤的标准治疗方法。本文综述了背阔肌纤维瘤的诊断、治疗和发病机制的最新进展。我们还讨论了近年来对背阔肌纤维瘤基因组改变认识的进展。
