Bıçakcı Nilüfer, Batı Fatih, Silov Güler, Kırtıloğlu Banu
Department of Nuclear Medicine, University of Health Sciences Türkiye, Samsun Training and Research Hospital, Samsun, Türkiye.
Department of Nuclear Medicine, Samsun University Faculty of Medicine, Samsun, Türkiye.
Turk J Surg. 2025 Sep 3;41(3):313-320. doi: 10.47717/turkjsurg.2025.2025-5-18. Epub 2025 Jul 11.
To evaluate the morphological and metabolic characteristics of incidentally detected elastofibroma dorsi (EFD) on F-18 florodeoksiglukoz (FDG) positron emission tomography/computed tomography (PET/CT) and their longitudinal changes in oncologic patients.
We retrospectively reviewed 42 197 PET/CT scans performed at our institution between January 2019 and September 2023. EFD was incidentally identified in 20 patients (0.05%). Patient demographics, primary malignancy, lesion localization, dimensions, and maximum standardized uptake values (SUV) were recorded. Measurements were obtained before treatment and at the next 3‑month follow‑up. Statistical analyses included Mann‑Whitney U, Shapiro-Wilk and Spearman correlation tests; significance was set at p<0.05.
The cohort comprised 17 females (85%) and 3 males (15%) with a median age of 67 years (range, 47-83). Primary diagnoses were breast cancer (n=8, 40%) and various other malignancies (n=12, 60%). Lesions were bilateral in 75% of cases. Pre‑treatment lesion size ranged from 10 to 55 mm; median SUV was 2.4 (right) and 2.5 (left). No significant differences in baseline size or SUV were observed between breast and other cancers. A moderate correlation existed between right and left SUV (r=0.641; p=0.010). After 3 months, only the left longest diameter showed a statistically significant decrease (median, 45.0 mm vs. 43.0 mm; p=0.034), which may reflect measurement variability or positional factors rather than true biological change. SUV values remained stable.
Incidentally detected EFD on PET/CT exhibits low to moderate and stable FDG uptake and predominantly bilateral localization. Recognition of its characteristic features can prevent unnecessary interventions.
评估在F-18氟脱氧葡萄糖（FDG）正电子发射断层扫描/计算机断层扫描（PET/CT）上偶然发现的背侧弹力纤维瘤（EFD）的形态学和代谢特征及其在肿瘤患者中的纵向变化。
我们回顾性分析了2019年1月至2023年9月在本机构进行的42197例PET/CT扫描。20例患者（0.05%）偶然发现了EFD。记录患者的人口统计学信息、原发性恶性肿瘤、病变定位、尺寸和最大标准化摄取值（SUV）。在治疗前和接下来的3个月随访时进行测量。统计分析包括曼-惠特尼U检验、夏皮罗-威尔克检验和斯皮尔曼相关性检验；显著性设定为p<0.05。
该队列包括17名女性（85%）和3名男性（15%），中位年龄为67岁（范围47-83岁）。原发性诊断为乳腺癌（n=8，40%）和各种其他恶性肿瘤（n=12，60%）。75%的病例病变为双侧。治疗前病变大小范围为10至55毫米；中位SUV右侧为2.4，左侧为2.5。乳腺癌和其他癌症之间在基线大小或SUV方面未观察到显著差异。左右SUV之间存在中度相关性（r=0.641；p=0.010）。3个月后，只有左侧最长径显示出统计学上的显著减小（中位值，45.0毫米对43.0毫米；p=0.034），这可能反映了测量变异性或位置因素，而非真正的生物学变化。SUV值保持稳定。
PET/CT上偶然发现的EFD表现出低至中度且稳定的FDG摄取，且主要为双侧定位。认识其特征可避免不必要的干预。
