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舌尖部口腔弹力纤维瘤样病变:一例报告及文献复习

Oral Elastofibromatous Lesion on the Tip of the Tongue: A Case Report and a Literature Review.

作者信息

Toida Makoto, Hayashi Itsuki, Yamaguchi Aina, Naiki Hironobu

机构信息

Department of Oral and Maxillofacial Surgery, Sugita Genpaku Memorial Obama Public Hospital, Obama, JPN.

Department of Oral and Maxillofacial Surgery, Gifu University, Gifu, JPN.

出版信息

Cureus. 2024 Jul 26;16(7):e65430. doi: 10.7759/cureus.65430. eCollection 2024 Jul.

DOI:10.7759/cureus.65430
PMID:39188483
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11346676/
Abstract

Oral elastofibromatous lesions (OEFLs) are rare benign tumor-like lesions of the oral cavity, which are characterized by marked hyperplasia of elastic fibers. A case of OEFL on the tip of the tongue of an 83-year-old male is presented. The lesion was a painless, yellowish-white, smooth-surfaced, elastic-soft, well-demarcated, slightly flattened, round plaque-like mucosal lesion, measuring about 4 x 3 mm. The lesion was excised under local anesthesia with the clinical diagnosis of an irritation fibroma and a benign tumor including a lipoma, and diagnosed histopathologically as an OEFL. Four years and nine months after the surgery, no abnormality was observed at the surgical site, and there were no signs of recurrence. In addition to a report of the case, the clinical and histopathological features of 14 similar cases reported in the English literature were reviewed.

摘要

口腔弹性纤维瘤样病变(OEFLs)是口腔中罕见的良性肿瘤样病变,其特征为弹性纤维显著增生。本文报告一例83岁男性舌尖部的OEFL。病变为无痛性、黄白色、表面光滑、质地柔软有弹性、边界清晰、略扁平的圆形斑块状黏膜病变,大小约4×3mm。该病变在局部麻醉下切除,临床诊断为刺激性纤维瘤及包括脂肪瘤在内的良性肿瘤,组织病理学诊断为OEFL。术后四年零九个月,手术部位未观察到异常,也无复发迹象。除该病例报告外,还对英文文献中报道的14例类似病例的临床和组织病理学特征进行了回顾。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36d8/11346676/8fb261c03cf3/cureus-0016-00000065430-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36d8/11346676/a1ffc2adb6b9/cureus-0016-00000065430-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36d8/11346676/18982a623939/cureus-0016-00000065430-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36d8/11346676/8fb261c03cf3/cureus-0016-00000065430-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36d8/11346676/a1ffc2adb6b9/cureus-0016-00000065430-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36d8/11346676/18982a623939/cureus-0016-00000065430-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36d8/11346676/8fb261c03cf3/cureus-0016-00000065430-i03.jpg

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本文引用的文献

1
Rare papular presentation of an elastofibromatous lesion of the alveolar mucosa.罕见的肺泡黏膜弹性纤维瘤样病变呈丘疹样表现。
J Oral Sci. 2022 Jul 1;64(3):251-252. doi: 10.2334/josnusd.21-0461. Epub 2022 Apr 29.
2
Current Update on the Diagnosis, Management and Pathogenesis of Elastofibroma Dorsi.当前关于背阔肌弹力纤维瘤的诊断、治疗和发病机制的最新研究进展。
Anticancer Res. 2021 May;41(5):2211-2215. doi: 10.21873/anticanres.14997.
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Identification of elastofibroma and elastofibroma-like lesions in cases diagnosed as oral fibromas.
在诊断为口腔纤维瘤的病例中识别弹性纤维瘤和弹性纤维瘤样病变。
Biotech Histochem. 2021 Nov;96(8):608-615. doi: 10.1080/10520295.2021.1882699. Epub 2021 Feb 19.
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Elastofibromatous lesion as a differential diagnosis of white lesions of the oral mucosa.弹性纤维瘤样病变作为口腔黏膜白色病变的鉴别诊断。
J Cutan Pathol. 2020 Mar;47(3):307-310. doi: 10.1111/cup.13634. Epub 2019 Dec 30.
5
Intraoral epidermoid cyst with extensive elastofibromatous changes: an unusual finding.伴有广泛弹性纤维瘤样改变的口腔表皮样囊肿:一项不寻常的发现。
Oral Maxillofac Surg. 2019 Dec;23(4):493-497. doi: 10.1007/s10006-019-00785-y. Epub 2019 Jun 6.
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Elastofibroma oralis.口腔弹力纤维瘤
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Oral elastofibromatous lesions: a review and case series.口腔弹性纤维瘤样病变:综述与病例系列
Head Neck Pathol. 2011 Sep;5(3):254-8. doi: 10.1007/s12105-011-0274-y. Epub 2011 Jun 18.
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Elastofibromatous change of the oral mucosa: case report and literature review.口腔黏膜弹性纤维瘤样改变:病例报告及文献综述
J Cutan Pathol. 2010 Oct;37(10):1067-71. doi: 10.1111/j.1600-0560.2010.01576.x. Epub 2010 Jun 23.
9
Elastofibromatous changes and hyperelastosis of the oral mucosa.口腔黏膜的弹性纤维瘤样改变和弹性组织增生
Head Neck Pathol. 2010 Mar;4(1):31-6. doi: 10.1007/s12105-009-0153-y. Epub 2009 Nov 27.
10
Elastofibroma presenting as an oral soft tissue mass.
J Oral Pathol Med. 2008 Feb;37(2):125-6. doi: 10.1111/j.1600-0714.2007.00592.x.