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“游泳神经元”的整合神经科学

Integrative Neuroscience of , a "Swimming Neuron".

作者信息

Brette Romain

机构信息

Sorbonne Université, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, Institut de la Vision, Paris 75012, France

出版信息

eNeuro. 2021 Jun 7;8(3). doi: 10.1523/ENEURO.0018-21.2021. Print 2021 May-Jun.

DOI:10.1523/ENEURO.0018-21.2021
PMID:33952615
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8208649/
Abstract

is a unicellular organism that swims in fresh water by beating thousands of cilia. When it is stimulated (mechanically, chemically, optically, thermally…), it often swims backward then turns and swims forward again. This "avoiding reaction" is triggered by a calcium-based action potential. For this reason, some authors have called a "swimming neuron." This review summarizes current knowledge about the physiological basis of behavior of .

摘要

是一种单细胞生物,通过摆动数千根纤毛在淡水中游动。当它受到刺激(机械、化学、光学、热……)时,它常常会向后游动,然后转身再次向前游动。这种“回避反应”由基于钙的动作电位触发。因此,一些作者称其为“游动神经元”。这篇综述总结了关于其行为生理基础的当前知识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c7/8208649/031d5c877629/ENEURO.0018-21.2021_f014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c7/8208649/c83b89dc2e22/ENEURO.0018-21.2021_f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c7/8208649/1a07f16d2179/ENEURO.0018-21.2021_f002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c7/8208649/d32b9b15bbe5/ENEURO.0018-21.2021_f003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c7/8208649/093d0a8e279f/ENEURO.0018-21.2021_f004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c7/8208649/156e66741611/ENEURO.0018-21.2021_f005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c7/8208649/e3eba8408955/ENEURO.0018-21.2021_f006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c7/8208649/e194555751ad/ENEURO.0018-21.2021_f007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c7/8208649/2df05f3d50d6/ENEURO.0018-21.2021_f008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c7/8208649/cab34798c156/ENEURO.0018-21.2021_f009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c7/8208649/cb37ccb9c4ed/ENEURO.0018-21.2021_f010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c7/8208649/8705368ead40/ENEURO.0018-21.2021_f011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c7/8208649/88b230e42725/ENEURO.0018-21.2021_f012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c7/8208649/810cc38fccc2/ENEURO.0018-21.2021_f013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c7/8208649/031d5c877629/ENEURO.0018-21.2021_f014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c7/8208649/c83b89dc2e22/ENEURO.0018-21.2021_f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c7/8208649/1a07f16d2179/ENEURO.0018-21.2021_f002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c7/8208649/d32b9b15bbe5/ENEURO.0018-21.2021_f003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c7/8208649/093d0a8e279f/ENEURO.0018-21.2021_f004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c7/8208649/156e66741611/ENEURO.0018-21.2021_f005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c7/8208649/e3eba8408955/ENEURO.0018-21.2021_f006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c7/8208649/e194555751ad/ENEURO.0018-21.2021_f007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c7/8208649/2df05f3d50d6/ENEURO.0018-21.2021_f008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c7/8208649/cab34798c156/ENEURO.0018-21.2021_f009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c7/8208649/cb37ccb9c4ed/ENEURO.0018-21.2021_f010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c7/8208649/8705368ead40/ENEURO.0018-21.2021_f011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c7/8208649/88b230e42725/ENEURO.0018-21.2021_f012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c7/8208649/810cc38fccc2/ENEURO.0018-21.2021_f013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c7/8208649/031d5c877629/ENEURO.0018-21.2021_f014.jpg

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2
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3
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4
Extracellular Interaction of , ATP and Phage 0105phi7-2: A Potential New Anti-Bacterial Strategy.细胞外相互作用的研究,ATP 和噬菌体 0105phi7-2:一种潜在的新的抗菌策略。
Viruses. 2023 Dec 12;15(12):2409. doi: 10.3390/v15122409.
5
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Anim Cogn. 2023 Nov;26(6):1837-1850. doi: 10.1007/s10071-023-01819-5. Epub 2023 Sep 4.
6
Perspectives on Principles of Cellular Behavior from the Biophysics of Protists.从原生生物物理学角度看细胞行为原理。
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7
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8
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Integr Comp Biol. 2023 Dec 29;63(6):1485-1508. doi: 10.1093/icb/icad075.
9
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10
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Microorganisms. 2023 Apr 3;11(4):937. doi: 10.3390/microorganisms11040937.
Elife. 2021 Jan 4;10:e61907. doi: 10.7554/eLife.61907.
4
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Proc Natl Acad Sci U S A. 2020 Dec 1;117(48):30201-30207. doi: 10.1073/pnas.2011146117. Epub 2020 Nov 16.
5
MEMBRANE POTENTIAL RESPONSES TO THERMAL STIMULATION AND THE CONTROL OF THERMOACCUMULATION IN PARAMECIUM CAUDATUM.尾草履虫对热刺激的膜电位反应及热蓄积的控制
J Exp Biol. 1992 Mar;164:39-53. doi: 10.1242/jeb.164.1.39.
6
A simple device to immobilize protists for electrophysiology and microinjection.一种用于固定原生动物以进行电生理学和微注射的简单装置。
J Exp Biol. 2020 Jun 17;223(Pt 12):jeb219253. doi: 10.1242/jeb.219253.
7
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Elife. 2019 Dec 23;8:e50084. doi: 10.7554/eLife.50084.
8
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9
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10
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