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[运用物理化学和免疫吸附法对从烧伤皮肤分离出的一种毒素的生物活性进行的比较研究]

[Comparative study of the biological activity of a toxin isolated from burned skin using physicochemical and immunosorption methods].

作者信息

Movshev B E, Nedoshivina R V

出版信息

Vopr Med Khim. 1977 Sep-Oct;23(5):685-9.

PMID:339531
Abstract

Highly specific isolation of a toxin from an extract of burned skin was achieved by means of antibodies immobilized on nonsoluble carrier (immunosorbent). The stability of the pure toxin distinctly decreased on storage. The interrelations were studied between manifestations of the biological activity of the toxin preparations and immunochemical purity of the toxin as well as addition of serum albumin.

摘要

通过固定在不溶性载体(免疫吸附剂)上的抗体,从烧伤皮肤提取物中实现了对毒素的高度特异性分离。纯毒素在储存时稳定性明显降低。研究了毒素制剂的生物活性表现与毒素的免疫化学纯度以及血清白蛋白添加之间的相互关系。

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