Martinez J L, Weinberger S B
Department of Psychology, University of California, Berkeley 94720.
Behav Neurosci. 1988 Jun;102(3):404-8. doi: 10.1037//0735-7044.102.3.404.
A very high correlation was found in rats between latency to escape on the first trial of an active avoidance task and the rate at which [leu]enkephalin is hydrolyzed in plasma. In addition, the rate of [leu]enkephalin hydrolysis is significantly altered following the first training trial. The results suggest that a regulatory enzyme system exists for [leu]enkephalin in plasma and that this system may be important for modulating behavior.
在大鼠身上发现，主动回避任务首次试验中的逃避潜伏期与血浆中亮氨酸脑啡肽的水解速率之间存在非常高的相关性。此外，首次训练试验后，亮氨酸脑啡肽的水解速率发生了显著变化。结果表明，血浆中存在一种针对亮氨酸脑啡肽的调节酶系统，该系统可能对调节行为很重要。
