Department of Population Science, American Cancer Society, Atlanta, GA, USA.
Departments of Neurology and Rehabilitation Medicine, Emory University, Atlanta, GA, USA.
Int J Behav Med. 2022 Apr;29(2):220-229. doi: 10.1007/s12529-021-09999-5. Epub 2021 May 6.
This pilot study explored the feasibility, acceptability, and usability of a web-based intervention for survivors of physical inactivity-related cancers through a two-arm, 12-week randomized controlled trial. Secondarily, this study tested the change in physical activity (PA) and sedentary time with intervention exposure.
Prior to randomization to the intervention (n = 45) or behavior "as usual" wait-listed control (n = 40) groups, participants completed baseline surveys and an accelerometer protocol. The intervention focused on increasing PA and decreasing sedentary time through social cognitive theory techniques. Follow-up acceptability/usability surveys (intervention group only) and accelerometers were sent after the intervention period. Information on intervention completion, adverse events, and user statistics were collected to determine feasibility. Median login time and mean acceptability/usability scores were calculated.
Participants (mean age = 60 ± 7 years) included female (n = 80, 94%) and male survivors of breast (82%), colon (6%), endometrial (6%), bladder (4%), and kidney (2%) cancer. Seventy-eight (91.7%) participants returned partially or fully complete post-intervention data. There were no reported injuries or safety concerns. Intervention participants logged into the website for a total of 95 min (Q1, Q3 = 11, 204). System usability scores (72 ± 3) indicated above average usability of the website. Changes in time spent active and sedentary were not statistically significantly different between groups (p = 0.45), but within-group changes suggested intervention group participants spent more time active and less time sedentary after the intervention.
Results of this pilot study suggest its feasibility and acceptability for survivors of several inactivity-related cancers. Additional research to determine long-term efficacy is warranted. This low-cost online-only intervention has the potential to have a very broad reach.
Clinical Trials Number: NCT03983083. Date registered: June 12th, 2019.
本研究通过一项为期 12 周的两臂随机对照试验，探索了针对缺乏运动相关癌症幸存者的基于网络的干预措施的可行性、可接受性和实用性。其次，本研究测试了干预措施暴露后身体活动（PA）和久坐时间的变化。
在随机分配到干预组（n=45）或行为“照常”候补对照组（n=40）之前，参与者完成基线调查和加速度计方案。干预措施侧重于通过社会认知理论技术增加 PA 和减少久坐时间。干预后，仅向干预组发送后续接受度/实用性调查（接受度/实用性调查）和加速度计。收集有关干预完成情况、不良事件和用户统计数据的信息，以确定可行性。计算中位数登录时间和平均接受度/实用性评分。
参与者（平均年龄 60 ± 7 岁）包括女性（n=80，94%）和男性乳腺癌（82%）、结肠癌（6%）、子宫内膜癌（6%）、膀胱癌（4%）和肾癌（2%）幸存者。78（91.7%）名参与者返回部分或完全完整的干预后数据。没有报告受伤或安全问题。干预组参与者总共登录网站 95 分钟（Q1，Q3=11，204）。系统可用性评分（72 ± 3）表明网站的可用性高于平均水平。组间时间花费在活跃和久坐上的变化无统计学意义（p=0.45），但组内变化表明干预组参与者在干预后花更多的时间活跃和更少的时间久坐。
这项初步研究的结果表明，它对几种与缺乏运动相关的癌症幸存者具有可行性和可接受性。需要进一步研究以确定长期疗效。这种低成本的在线干预措施具有广泛应用的潜力。
临床试验编号：NCT03983083。注册日期：2019 年 6 月 12 日。
