Department of Veterinary Medicine and Epidemiology, University of California Davis, Davis, California, USA.
Koret School of Veterinary Medicine, The Robert H. Smith Faculty of Agriculture, Food and Environment, Hebrew University of Jerusalem, Rehovot, Israel.
J Vet Intern Med. 2021 May;35(3):1397-1405. doi: 10.1111/jvim.16121. Epub 2021 May 6.
Urolithiasis is an important upper and lower urinary tract disease in cats that results in morbidity and mortality.
To describe trends in composition of uroliths in cats and evaluate risk factors related to age, breed, sex, urolith location, and bacterial urolith cultures.
A total of 3940 uroliths and the cats from which they were obtained.
The database of the UC Davis Gerald V. Ling Urinary Stone Analysis Laboratory was searched for all urolith submissions from cats between January 2005 and December 2018. Mineral type, age, breed, sex, and urolith location and culture results were recorded. Trends were evaluated and variables compared to evaluate risk factors.
A significant decrease in the proportion of calcium oxalate (CaOx)-containing uroliths occurred over time (P = .02), from 50.1% (204/407) of all submissions in 2005 to 37.7% (58/154) in 2018. In contrast, the proportion of struvite-containing uroliths increased significantly (P = .002), from 41.8% (170/407) in 2005 to 54.5% (84/154) in 2018. The proportion of CaOx-containing uroliths in the upper urinary tract was significantly higher compared to the proportion of other urolith types in the upper urinary tract. Urate-containing uroliths were the third most common type (361/3940, 9.2%). Overall, sex and age predispositions were similar to those reported previously.
The decrease in the proportion of CaOx-containing uroliths and increase in the proportion of struvite-containing uroliths warrants investigation. Further education regarding the efficacy of medical dissolution of struvite-containing uroliths is recommended.
尿石症是猫上下尿路的一种重要疾病，可导致发病率和死亡率。
描述猫尿石成分的变化趋势，并评估与年龄、品种、性别、尿石位置和细菌尿石培养相关的危险因素。
总共 3940 个尿石及其来源猫。
检索加利福尼亚大学戴维斯分校 Gerald V. Ling 尿液结石分析实验室的数据库，以获取 2005 年 1 月至 2018 年 12 月期间所有猫的尿石送检。记录矿物类型、年龄、品种、性别、尿石位置和培养结果。评估趋势并比较变量以评估危险因素。
随着时间的推移，含钙草酸钙（CaOx）的尿石比例显著下降（P =.02），从 2005 年所有送检物的 50.1%（204/407）降至 2018 年的 37.7%（58/154）。相比之下，含鸟粪石的尿石比例显著增加（P =.002），从 2005 年的 41.8%（170/407）增至 2018 年的 54.5%（84/154）。与其他类型的上尿路结石相比，上尿路中含钙草酸钙的尿石比例明显更高。尿酸盐结石是第三常见类型（361/3940，9.2%）。总体而言，性别和年龄的易感性与之前报道的相似。
含钙草酸钙的尿石比例下降，含鸟粪石的尿石比例增加，值得进一步研究。建议进一步教育有关溶解含鸟粪石尿石的效果。
