Ritchie P A, Cheshire M A, Pearce N H
Sir Humphry Davy Department of Anaesthesia, University of Bristol, Bristol Royal Infirmay.
Br J Anaesth. 1988 Jun;60(7):859-63. doi: 10.1093/bja/60.7.859.
The contamination of four types of anaesthetic machine with halothane was sequentially sampled by mass spectrometry while the machines were continuously flushed with oxygen 8 litre min-1 for up to 24 h. Contamination decreased in an exponential manner. Machines fitted with Selectatec vaporizer mounting systems and with the vaporizer removed showed contamination less than 0.02 parts per million (p.p.m.) of halothane after 12 h flushing. Machines with cage-mounted vaporizers or with vaporizers left connected to the Selectatec block demonstrated persisting contamination. The Fluotec Mk.4 vaporizer showed an improvement on earlier designs in this respect. Background contamination concentrations of greater than 0.05 p.p.m. were measured in a patient-free recovery area of an operating theatre suite. Concentrations increased to 1 p.p.m. when patients were admitted following halothane anaesthesia. Decontamination of anaesthetic machines to concentrations of halothane below those detected as background contamination within recovery areas may allow such machines to be used safely to anaesthetize patients at risk from halothane.
使用质谱仪对四种类型的麻醉机中氟烷污染情况进行了连续采样,同时这些麻醉机以8升/分钟的氧气持续冲洗长达24小时。污染呈指数方式下降。配备Selectatec蒸发器安装系统且移除蒸发器的麻醉机在冲洗12小时后,氟烷污染显示低于百万分之0.02(ppm)。带有笼式安装蒸发器的麻醉机或蒸发器仍连接到Selectatec模块的麻醉机显示出持续的污染。Fluotec Mk.4蒸发器在这方面比早期设计有所改进。在手术室套房的无患者恢复区域测量到背景污染浓度大于百万分之0.05(ppm)。当氟烷麻醉后的患者进入时,浓度增加到百万分之一(ppm)。将麻醉机的氟烷浓度净化至低于在恢复区域检测为背景污染的浓度,可能会使此类麻醉机能够安全地用于麻醉有氟烷风险的患者。