Hu Xinwei, Tan Zheng, Xiong Li, Yang Can, Jiang Huanfeng, Zeng Wei
Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510641, China.
Org Lett. 2021 May 21;23(10):3965-3969. doi: 10.1021/acs.orglett.1c01132. Epub 2021 May 6.
A Rh(III)-catalyzed Csp-Csp σ-bond carbenoid functionalization of α-(2-indolyl)alcohols with acceptor/acceptor diazo compounds has been developed. This transformation provides an efficient strategy to assemble stable C2-enolated indole skeletons via Csp-Csp σ-bond cleavage.
已开发出一种铑（III）催化的α-（2-吲哚基）醇与受体/受体重氮化合物的Csp-Csp σ键类卡宾官能团化反应。这种转化提供了一种通过Csp-Csp σ键裂解来组装稳定的C2-烯醇化吲哚骨架的有效策略。
